Evidence map›Paper›PMID 30841024›Full record

ArticleMolecules and cells2019

Enhanced Expression and Functional Characterization of the Recombinant Putative Lysozyme-PMAP36 Fusion Protein.

Zhili Rao, So Young Kim, Md Rashedunnabi Akanda, Su Jin Lee, In Duk Jung, Byung-Yong Park, Seralathan Kamala-Kannan, Jin Hur, Jung Hee Park

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules and cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Zhili RaoDivision of Biotechnology, College of Environmental & Bioresources Sciences, Chonbuk National University, Iksan 54596, Korea.
So Young KimDivision of Biotechnology, College of Environmental & Bioresources Sciences, Chonbuk National University, Iksan 54596, Korea.
Md Rashedunnabi AkandaCollege of Veterinary Medicine and Bio-safety Research Institute, Chonbuk National University, Iksan 54596, Korea.
Su Jin LeeDepartment of Immunology, Laboratory of Dendritic Cell Differentiation and Regulation, School of Medicine, Konkuk University, Chungju 27478, Korea.
In Duk JungDepartment of Immunology, Laboratory of Dendritic Cell Differentiation and Regulation, School of Medicine, Konkuk University, Chungju 27478, Korea.
Byung-Yong ParkCollege of Veterinary Medicine and Bio-safety Research Institute, Chonbuk National University, Iksan 54596, Korea.
Seralathan Kamala-KannanDivision of Biotechnology, College of Environmental & Bioresources Sciences, Chonbuk National University, Iksan 54596, Korea.
Jin HurVeterinary Public Health, College of Veterinary Medicine, Chonbuk National University, Iksan 54596, Korea.
Jung Hee ParkDivision of Biotechnology, College of Environmental & Bioresources Sciences, Chonbuk National University, Iksan 54596, Korea.
Jeonbuk National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The porcine myeloid antimicrobial peptide (PMAP), one of the cathelicidin family members, contains small cationic peptides with amphipathic properties. We used a putative lysozyme originated from the bacteriophage P22 (P22 lysozyme) as a fusion partner, which was connected to the N-terminus of the PMAP36 peptide, to markedly increase the expression levels of recombinant PMAP36. The PMAP36-P22 lysozyme fusion protein with high solubility was produced in

Indexed as

AnimalsAnti-Infective AgentsAntimicrobial Cationic PeptidesBacteriaCathelicidinsCell Membrane PermeabilityFemaleHemolysisImmunologic FactorsMice, Inbred C57BLMicrobial Sensitivity TestsMuramidasePlasmidsProtein Structure, SecondaryRecombinant Fusion ProteinsSwineAnti-Infective AgentsAntimicrobial Cationic PeptidesCathelicidinsImmunologic FactorsMuramidaseRecombinant Fusion Proteinscircular dichroism spectroscopyhemolytic activityminimum inhibitory concentrationporcine myeloid antimicrobial peptidetransmission electron microscope

Identifiers

PMID30841024
PMCPMC6449713
OpenAlexW2962916939

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.