Evidence map›Paper›PMID 30840883›Full record

ArticleCell reports2019

Ultra-High-Frequency Reprogramming of Individual Long-Term Hematopoietic Stem Cells Yields Low Somatic Variant Induced Pluripotent Stem Cells.

Kai Wang, Anthony K Guzman, Zi Yan, Shouping Zhang, Michael Y Hu, Mehdi B Hamaneh, Yi-Kuo Yu, Seda Tolu, Jinghang Zhang, Holly E Kanavy and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. How Does Reprogramming to Pluripotency Affect Genomic Imprinting?Frontiers in cell and developmental biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Kai WangDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, NY.
Anthony K GuzmanDepartment of Internal Medicine, Division of Dermatology, Albert Einstein College of Medicine, Bronx, NY.
Zi YanDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, NY.
Shouping ZhangDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, NY.
Michael Y HuDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, NY.
Mehdi B HamanehNational Center for Biotechnology Information, National Library of Medicine, Bethesda, MD.
Yi-Kuo YuNational Center for Biotechnology Information, National Library of Medicine, Bethesda, MD.
Seda ToluDepartment of Internal Medicine, Division of Dermatology, Albert Einstein College of Medicine, Bronx, NY.
Jinghang ZhangDepartment of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, NY.
Holly E KanavyDepartment of Internal Medicine, Division of Dermatology, Albert Einstein College of Medicine, Bronx, NY.
Kenny YeDepartment of Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY.
Boris BartholdyDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, NY.
Eric E BouhassiraDepartment of Cell Biology, Albert Einstein College of Medicine, Bronx, NY. Electronic address: eric.bouhassira@einstein.yu.edu.
Albert Einstein College of Medicine · USNational Center for Biotechnology Information · US

Funding

Robust Accurate Identification of peptides from tandem mass spectrometry dataZIALM092404 · NLM · NATIONAL LIBRARY OF MEDICINE · PI YU, YI-KUO · 2009 to 2025
$13.2M
Production of Cultured Red Blood CellsR01HL130764 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Eric E. Bouhassira · 2015 to 2026
$6.5M
NHLBI NIH HHS R01 HL130764
6 · The paper itself

Abstract

Efficiency of reprogramming of human cells into induced pluripotent stem cells (iPSCs) has remained low. We report that individual adult human CD49f

Indexed as

AdolescentAdultCellular ReprogrammingFemaleHealthy VolunteersHematopoietic Stem CellsHumansInduced Pluripotent Stem CellsMaleMiddle AgedYoung Adultinduced pluripotent stem cellslong-term hematopoietic stem cellsreprogrammingskin fibroblastssomatic mutation

Identifiers

PMID30840883
PMCPMC6754097
OpenAlexW2919025967

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.