ArticleInflammatory bowel diseases2019
Initial Assessment of Post-traumatic Stress in a US Cohort of Inflammatory Bowel Disease Patients.
Article in Inflammatory bowel diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.
- Association between depression and anxiety with the risk and flare of inflammatory bowel disease: a systematic review and meta-analysis.Internal and emergency medicine · 2025Pooled it
- Exploring the interplay between posttraumatic stress disorder, gut microbiota, and inflammatory biomarkers: a comprehensive meta-analysis.Frontiers in immunology · 2024Pooled it
- Prevalence and Impact of Post-traumatic Stress Disorder in Gastrointestinal Conditions: A Systematic Review.Digestive diseases and sciences · 2021Pooled it
- Trial
- Adverse Childhood Experiences and Disease Activity Are Associated with Post-Traumatic Stress Symptoms in Crohn's Disease.Advances in therapy · 2026Article
- Can Mindfulness-Based Interventions Be Used to Treat PTSD-derived GI Disruptions in Black Women? A Review of Current Literature.Journal of racial and ethnic health disparities · 2026Review
- Managing Acute Severe Ulcerative Colitis in 2025 and Beyond.Current gastroenterology reports · 2026Review
- "Ulcerative Colitis and Irritable Bowel Syndrome Are Diagonally Opposite." Missing the Trees for the Woods.Journal of neurogastroenterology and motility · 2025Article
- Crohn's disease onset associated with a ballistic injury to the abdomen in the patient wounded in the war in Ukraine: a case report.Journal of medical case reports · 2025Article
- The War in Gaza and Barriers to Inflammatory Bowel Disease Care.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Post-traumatic stress disorder symptoms in Crohn's disease patients following surgery: a cross-sectional study.Therapeutic advances in gastroenterology · 2025Article
- "It's a tool, it's got hardships": a qualitative study of patient experience of colonoscopy and implications for trauma-informed care.Therapeutic advances in gastroenterology · 2025Article
- Implementation of a Trauma-Informed Care Approach in a Gastroenterology Setting.Digestive diseases and sciences · 2025Article
- Manifestations of and factors influencing posttraumatic growth among Chinese Crohn's disease patients: a qualitative exploration.International journal of qualitative studies on health and well-being · 2024Article
- Understanding the Perspectives and Experiences of Patients with Acute Severe Ulcerative Colitis in the Hospital: A Qualitative Analysis.Digestive diseases and sciences · 2024Article
- Self-care in patients affected by inflammatory bowel disease and caregiver contribution to self-care (IBD-SELF): a protocol for a longitudinal observational study.BMJ open gastroenterology · 2024Observational
- Clinical Education: Psychosocial Assessment and Treatment Planning for Patients with Inflammatory Bowel Disease.Journal of clinical psychology in medical settings · 2024Article
- Peri-Operative Optimization of Patients with Crohn's Disease.Current gastroenterology reports · 2024Review
- Risk of autoimmune diseases after post-traumatic stress disorder: a nationwide cohort study.European archives of psychiatry and clinical neuroscience · 2024Article
- Post-traumatic stress disorder symptoms are frequent among inflammatory bowel disease patients of South Asian descent-A case-control study.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundPost-traumatic stress (PTS), or the psycho-physiological response to a traumatic or life-threatening event, is implicated in medical patient outcomes. Emerging evidence suggests a complex relationship between PTS, the brain-gut axis, the gut microbiome, and immune function. Inflammatory bowel disease (IBD) may be susceptible to PTS and its subsequent impacts. To date, no study has evaluated PTS in IBD in the United States.
methodsAdult patients with IBD were recruited from an outpatient gastroenterology practice, via social media, and via a research recruitment website. Patients with irritable bowel syndrome (IBS) were recruited as a comparison group. Participants completed demographic and disease information, surgical and hospitalization history, and the PTSD Checklist-Civilian Version (PCL-C). Statistical analyses evaluated rates of PTS in IBD and IBS, including differences between groups for PTS severity. Regression analyses determined potential predictors of PTS.
resultsOne hundred eighty-eight participants (131 IBD, 57 IBS) completed the study. Thirty-two percent of IBD and 26% of IBS patients met the criteria for significant PTS symptoms based on PCL-C cutoffs. Inflammatory bowel disease patients are more likely to attribute PTS to their disease than IBS patients. Crohn's disease (CD) patients appear to be the most likely to experience PTS, including those being hospitalized or undergoing ileostomy surgery. Symptom severity is the greatest predictor of PTS for ulcerative colitis and IBS.
conclusionsAlthough PTS is relevant in both IBS and IBD, IBD patients are seemingly more susceptible to PTS due their disease experiences, especially CD patients. The nature of PTS symptoms may contribute to IBD disease processes, most notably through sleep disturbance and ANS arousal. Clinicians should assess for PTS in IBD patients as standard of care, especially after a hospitalization or surgery.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.