Evidence map›Paper›PMID 30840728›Full record

ArticleJournal of medical imaging (Bellingham, Wash.)2018

Prostate cancer detection from multi-institution multiparametric MRIs using deep convolutional neural networks.

Yohan Sumathipala, Nathan Lay, Baris Turkbey, Clayton Smith, Peter L Choyke, Ronald M Summers

Erratum issuedAbstract read
In one paragraph

Article in Journal of medical imaging (Bellingham, Wash.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. IR-GPT: AI Foundation Models to Optimize Interventional Radiology.Cardiovascular and interventional radiology · 2025
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  20. Artificial intelligence at the intersection of pathology and radiology in prostate cancer.Diagnostic and interventional radiology (Ankara, Turkey) · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Yohan SumathipalaNational Institutes of Health Clinical Center, Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, Bethesda, Maryland, United States.ORCID https://orcid.org/0000-0001-5260-0540
Nathan LayNational Institutes of Health Clinical Center, Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, Bethesda, Maryland, United States.
Baris TurkbeyNational Institutes of Health, National Cancer Institute, Molecular Imaging Program, Bethesda, Maryland, United States.
Clayton SmithNational Institutes of Health, National Cancer Institute, Molecular Imaging Program, Bethesda, Maryland, United States.
Peter L ChoykeNational Institutes of Health, National Cancer Institute, Molecular Imaging Program, Bethesda, Maryland, United States.
Ronald M SummersNational Institutes of Health Clinical Center, Imaging Biomarkers and Computer-Aided Diagnosis Laboratory, Radiology and Imaging Sciences, Bethesda, Maryland, United States.ORCID https://orcid.org/0000-0001-8081-7376

Funding

Prostate Cancer ImagingZIABC010655 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHOYKE, PETER L · 2009 to 2025
$49.2M
Computer Aided Detection for Radiologic ImagesZ01CL040004 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2003 to 2008
$41k
Computer Aided Detection for Radiologic ImagesZIACL040004 · CLC · CLINICAL CENTER · PI SUMMERS, RONALD M. · 2009 to 2025
$0k
Intramural NIH HHS Z01 CL040004
6 · The paper itself

Abstract

Multiparametric magnetic resonance imaging (mpMRI) of the prostate aids in early diagnosis of prostate cancer, but is difficult to interpret and subject to interreader variability. Our objective is to generate probability maps, overlaid on original mpMRI images to help radiologists identify where a cancer is suspected as a computer-aided diagnostic (CAD). We optimized the holistically nested edge detection (HED) deep convolutional neural network. Our dataset contains T2, apparent diffusion coefficient, and high

Indexed as

computer-aided diagnosisdeep learningimage processingmagnetic resonance imagingneural networksprostate cancer

Identifiers

PMID30840728
PMCPMC6294844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.