Evidence map›Paper›PMID 30840707›Full record

ArticlePloS one2019

The role of the erythrocyte in the outcome of pregnancy with preeclampsia.

Márcia Aires Rodrigues de Freitas, Alice Vieira da Costa, Luciana Alves Medeiros, Lucas Moreira Cunha, Ubirajara Coutinho Filho, Mario da Silva Garrote Filho, Angélica Lemos Debs Diniz, Nilson Penha-Silva

Abstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
  6. The combination ofVeterinary world · 2021
    Article
  7. Article
  8. Methylation-dependent circulating microRNA 510 in preeclampsia patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Márcia Aires Rodrigues de FreitasDepartment of Gynecology and Obstetrics, Faculty of Medicine, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Alice Vieira da CostaInstitute of Biotechnology, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Luciana Alves MedeirosInstitute of Biotechnology, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Lucas Moreira CunhaInstitute of Biotechnology, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Ubirajara Coutinho FilhoFaculty of Chemical Engineering, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Mario da Silva Garrote FilhoInstitute of Biotechnology, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Angélica Lemos Debs DinizDepartment of Gynecology and Obstetrics, Faculty of Medicine, Federal University of Uberlândia, Uberlândia, MG, Brazil.
Nilson Penha-SilvaInstitute of Biotechnology, Federal University of Uberlândia, Uberlândia, MG, Brazil.ORCID 0000-0002-8205-6213

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this study was to analyze the relationships of osmotic and mechanical stability of erythrocytes with anthropometric, biochemical, hematologic and hemodynamic variables in pregnant women with preeclampsia (PE). The studied population consisted of 20 normotensive patients and 16 patients with PE. Patients with PE presented worse gestational outcome, greater hematologic impairment, erythrocytes osmotically more stable in vitro, but in conditions of isotonicity with the in vivo medium, in addition to hyperflow in orbital territory, when compared to normotensive patients. The correlation analysis between anthropometric, hematologic and hemodynamic variables in patients with PE indicated that erythrocytes with lower volumes and lower levels of hemoglobin favor the occurrence of a better gestational outcome, because they are more stable and because they are associated with a decrease in the hemodynamic changes present in the disease. This should mean that the tendency to microcytosis, probably due to a mechanism of compensatory mechanical selection, is a desirable characteristic in the disease.

Indexed as

Erythrocyte VolumeHemodynamicsPre-EclampsiaPregnancy OutcomeAdultBlood PressureCross-Sectional StudiesErythrocytesFemaleHumansPregnancy

Identifiers

PMID30840707
PMCPMC6402648

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.