Evidence map›Paper›PMID 30840455›Full record

ArticleThe Journal of organic chemistry2019

Concise Approach to Cyclohexyne and 1,2-Cyclohexadiene Precursors.

Jason V Chari, Francesca M Ippoliti, Neil K Garg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of organic chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Origins of Endo Selectivity in Diels-Alder Reactions of Cyclic Allene Dienophiles.Angewandte Chemie (International ed. in English) · 2021
    Article
  4. 1,2-Bis(arylthio)arene synthesis via aryne intermediates.Chemical communications (Cambridge, England) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jason V ChariDepartment of Biochemistry and Chemistry , University of California , Los Angeles , California 90095 , United States.
Francesca M IppolitiDepartment of Biochemistry and Chemistry , University of California , Los Angeles , California 90095 , United States.
Neil K GargDepartment of Biochemistry and Chemistry , University of California , Los Angeles , California 90095 , United States.ORCID 0000-0002-7793-2629

Funding

Time-of-Flight Mass Spectrometer for Synthesis Supporting Biomedical ResearchS10RR025631 · NCRR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HOUK, KENDALL N · 2009 to 2009
$328k
Harnessing Strained Intermediates to Access Complex MoleculesR01GM123299 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GARG, NEIL K · 2018 to 2018
$269k
NCRR NIH HHS S10 RR025631NIGMS NIH HHS R01 GM123299
6 · The paper itself

Abstract

Silyl triflate precursors to cyclic alkynes and allenes serve as valuable synthetic building blocks. We report a concise and scalable synthetic approach to prepare the silyl triflate precursors to cyclohexyne and 1,2-cyclohexadiene. The strategy involves a retro-Brook rearrangement of an easily accessible cyclohexanone derivative, followed by triflation protocols. This simple, yet controlled, method should enable the further study of strained alkynes and allenes in chemical synthesis.

Indexed as

AlkynesCyclohexenesMolecular StructureOrganosilicon Compounds1,4-cyclohexadieneAlkynesCyclohexenesOrganosilicon Compounds

Identifiers

PMID30840455
PMCPMC6935045

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.