Evidence map›Paper›PMID 30840252›Full record

ArticleEnvironmental science and pollution research international2019

Histopathological and biochemical studies on the effect of curcumin and taurine against bisphenol A toxicity in male rats.

Fatma Gökçe Apaydin, Ayşe Aslanturk, Meltem Uzunhisarcikli, Hatice Bas, Suna Kalender, Yusuf Kalender

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Can Antioxidants Reduce the Toxicity of Bisphenol?Antioxidants (Basel, Switzerland) · 2022
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Hepatoprotective effects of curcumin and taurine against bisphenol A-induced liver injury in rats.Environmental science and pollution research international · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fatma Gökçe ApaydinFaculty of Science, Department of Biology, Gazi University, Teknikokullar, 06500, Ankara, Turkey. fguzun@gazi.edu.tr.ORCID http://orcid.org/0000-0002-2771-7488
Ayşe AslanturkGazi University- Vocational High School of Health Services, Ankara, Turkey.
Meltem UzunhisarcikliGazi University- Vocational High School of Health Services, Ankara, Turkey.
Hatice BasFaculty of Arts and Science, Department of Biology, Bozok University, Yozgat, Turkey.
Suna KalenderFaculty of Gazi Education, Department of Science, Gazi University, Ankara, Turkey.
Yusuf KalenderFaculty of Science, Department of Biology, Gazi University, Teknikokullar, 06500, Ankara, Turkey.
Gazi University · TRYozgat Bozok Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA) is a chemical found in environmental xenoestrogen. In the present study, olive oil, curcumin, taurine, BPA, curcumin plus BPA, and taurine plus BPA were exposed to rats for 4 weeks via gavage. Content of malondialdehyde and activities of antioxidant enzymes (GPx, GST, SOD, CAT) and also histopathological and cytopathological changes of heart were studied. No significant changes in all studied parameters were seen between control, olive oil, curcumin, and taurine-treated groups. However, there were significant differences in levels of malondialdehyde and activities of antioxidant enzymes in BPA-exposed rats and some histo/cytopathological changes determined. In curcumin plus BPA-exposed and taurine plus BPA-exposed groups, we measured the preventive effects on some parameters but not exactly. As a result, curcumin and taurine significantly minimized BPA-induced cardiotoxicity in rats.

Indexed as

AnimalsAntioxidantsBenzhydryl CompoundsBisphenol A CompoundsCardiotoxicityCurcuminEnvironmental PollutantsHeartMaleMalondialdehydeOxidative StressPhenolsRatsRats, WistarTaurineAntioxidantsBenzhydryl Compoundsbisphenol ABisphenol A CompoundsCurcuminEnvironmental PollutantsMalondialdehydePhenolsTaurineBisphenol ACurcuminElectron microscopyHeartLight microscopyTaurine

Identifiers

PMID30840252
OpenAlexW2919670114

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.