ArticleGenetica2019
Characterization and phylogeny of bitter taste receptor genes (Tas2r) in Squamata.
Article in Genetica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Bitter taste receptors.Chemical senses · 2025Review
- Rapid expansion and specialization of the TAS2R bitter taste receptor family in amphibians.PLoS genetics · 2025Article
- The Remarkable Diversity of Vertebrate Bitter Taste Receptors: Recent Advances in Genomic and Functional Studies.International journal of molecular sciences · 2024Review
- Membrane-bound chemoreception of bitter bile acids and peptides is mediated by the same subset of bitter taste receptors.Cellular and molecular life sciences : CMLS · 2024Article
- Insights into the adaptive evolution of chromosome and essential traits through chromosome-level genome assembly ofiScience · 2024Article
- Evolutionary insights into umami, sweet, and bitter taste receptors in amphibians.Ecology and evolution · 2021Article
- Bitter taste receptors: Genes, evolution and health.Evolution, medicine, and public health · 2021Review
- The roles of genes in the bitter taste.AIMS genetics · 2019Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
The perception of bitter taste is linked to the detection of toxins. Therefore, it facilitates avoiding the consumption of potential toxins in the diet. At the molecular level, bitter taste is mediated by taste 2 receptors (Tas2rs). Studies on Tas2r have made major advances in recent years. However, little is known about Tas2rs in Squamata, the second largest order of extant vertebrates. To explore the repertoire and phylogenetic relationships among Tas2r genes in Squamata, we identified and characterized Tas2rs from genome assemblies of 15 Squamata species. We observed considerable Tas2r contraction and expansion in the suborders Serpentes and Lacertilia, respectively. Phylogenetic and reconciliation analysis suggested that lineage-specific gene gains and losses could have led to the Tas2r contraction and expansion in Squamata. Different Tas2r repertoires in Serpents and Lacertilia also reflect their oral anatomical features and taste behaviors. Our findings offer novel perspectives into the study of taste and dietary protection in Squamata species.
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Registered trials
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