Evidence map›Paper›PMID 30840155›Full record

ArticleJournal of materials science. Materials in medicine2019

Biofabrication of 3D cell-encapsulated tubular constructs using dynamic optical projection stereolithography.

Soham Wadnap, Srikumar Krishnamoorthy, Zhengyi Zhang, Changxue Xu

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 47 citations in OpenAlex.

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  13. Vascularization in tissue engineering: fundamentals and state-of-art.Progress in biomedical engineering (Bristol, England) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Soham WadnapDepartment of Industrial, Manufacturing, and Systems Engineering, Texas Tech University, Lubbock, TX, 79409, USA.
Srikumar KrishnamoorthyDepartment of Industrial, Manufacturing, and Systems Engineering, Texas Tech University, Lubbock, TX, 79409, USA.
Zhengyi ZhangSchool of Naval Architecture and Ocean Engineering, Huazhong University of Science and Technology, 430074, Wuhan, China. zhengyizhang@hust.edu.cn.
Changxue XuDepartment of Industrial, Manufacturing, and Systems Engineering, Texas Tech University, Lubbock, TX, 79409, USA. changxue.xu@ttu.edu.
Texas Tech University · USHuazhong University of Science and Technology · CN

Funding

Fundamental Research Funds for the Central Universities 2017KFYXJJ004National Natural Science Foundation of China 51709120
6 · The paper itself

Abstract

It has been widely recognized that one of the critical limitations in biofabrication of functional tissues/organs is lack of vascular networks which provide tissues and organs with oxygen and nutrients. Biofabrication of 3D vascular-like constructs is a reasonable first step towards successful printing of functional tissues and organs. In this paper, a dynamic optical projection stereolithography system has been implemented to successfully fabricate 3D Y-shaped tubular constructs with living cells encapsulated. The effects of operating conditions on the cure depth of a single layer have been investigated, such as UV intensity, exposure time, and cell density. A phase diagram has been constructed to identify optimal operating conditions. Cell viability immediately after printing has been measured to be around 75%. Post-printing mechanical properties, swelling properties, and microstructures of the gelatin methacrylate hydrogels have been characterized. The resulting fabrication knowledge helps to effectively and efficiently print tissue-engineered vascular networks with complex geometries.

Indexed as

AnimalsCells, CulturedCell SurvivalEquipment DesignExtracellular MatrixFibroblastsGelatinHumansHydrogelsMethacrylatesMiceNIH 3T3 CellsPrinting, Three-DimensionalRegenerative MedicineStereolithographyStress, MechanicalGelatinHydrogelsMethacrylates

Identifiers

PMID30840155
OpenAlexW2920887774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.