Evidence map›Paper›PMID 30840124›Full record

ArticleIntensive care medicine2019

Determinants of self-reported unacceptable outcome of intensive care treatment 1 year after discharge.

Monika C Kerckhoffs, Felicia F L Kosasi, Ivo W Soliman, Johannes J M van Delden, Olaf L Cremer, Dylan W de Lange, Arjen J C Slooter, Jozef Kesecioglu, Diederik van Dijk

Abstract read
In one paragraph

Article in Intensive care medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Trial
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  4. Redefining success: Incorporating long-term survival outcomes into routine benchmarking.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2025
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  8. Factors associated with racial and ethnic disparities in chronic pain after acute traumatic injury.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2024
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  9. It Is Feasible to Relieve Distressing Symptoms after the ICU.American journal of respiratory and critical care medicine · 2023
    Article
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  11. Critical care: A concept analysis.International journal of nursing sciences · 2023
    Review
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  13. Thirty years of ANZICS CORE: A clinical quality success story.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2023
    Article
  14. Article
  15. Article
  16. Article
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  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Monika C KerckhoffsDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Mail Stop F06.149, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands. m.c.kerckhoffs-2@umcutrecht.nl.ORCID 0000-0003-3280-7768
Felicia F L KosasiDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Mail Stop F06.149, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Ivo W SolimanDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Mail Stop F06.149, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Johannes J M van DeldenDepartment of Medical Humanities, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Olaf L CremerDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Mail Stop F06.149, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Dylan W de LangeDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Mail Stop F06.149, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Arjen J C SlooterDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Mail Stop F06.149, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Jozef KeseciogluDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Mail Stop F06.149, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.
Diederik van DijkDepartment of Intensive Care Medicine, University Medical Center Utrecht, Utrecht University, Mail Stop F06.149, P.O. Box 85500, 3508 GA, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSurvivors of critical illness often suffer from reduced health-related quality of life (HRQoL) due to long-term physical, cognitive, and mental health problems, also known as post-intensive care syndrome (PICS). Some intensive care unit (ICU) survivors even consider their state of health unacceptable. The aim of this study was to investigate the determinants of self-reported unacceptable outcome of ICU treatment.

methodsPatients who were admitted to the ICU for at least 48 h and survived the first year after discharge completed validated questionnaires on overall HRQoL and the components of PICS and stated whether they considered their current state of health an acceptable outcome of ICU treatment. The effects of overall HRQoL and components of PICS on unacceptable outcome were studied using multiple logistic regression analysis.

resultsOf 1453 patients, 67 (5%) reported their health state an unacceptable outcome of ICU treatment. These patients had a lower score on overall HRQoL (EQ-5D-index value of 0.57 vs. 0.81; p < 0.001), but we could not determine a cutoff value of the EQ-5D-index value that reliably identified unacceptable outcome. In the multivariate analysis, only the hospital anxiety and depression scale was significantly associated with an unacceptable outcome (OR 2.06, 99% CI 1.18-3.61).

conclusionsAlthough there is a strong association between low overall HRQoL and self-reported unacceptable outcome of ICU treatment, patients with low overall HRQoL may still consider their outcome acceptable. The mental component of PICS, but not the physical and cognitive component, is strongly associated with self-reported unacceptable outcome.

Indexed as

Patient Outcome AssessmentSelf ReportTime FactorsAgedAged, 80 and overFemaleHumansIntensive Care UnitsLength of StayMaleMiddle AgedPatient DischargePsychometricsQuality of LifeSurveys and QuestionnairesSurvivorsEthicsHealth-related quality of lifeLong-term outcomePatient-reported outcome measurePost-intensive care syndrome

Identifiers

PMID30840124
PMCPMC6534510

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.