Evidence map›Paper›PMID 30839831›Full record

ArticleApplied network science2018

A spatially heterogeneous network-based metapopulation software model applied to the simulation of a pulmonary tuberculosis infection.

Michael J Pitcher, Ruth Bowness, Simon Dobson, Stephen H Gillespie

Abstract read
In one paragraph

Article in Applied network science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael J Pitcher1School of Computer Science, University of St Andrews, North Haugh, St Andrews, UK.ORCID 0000-0002-1935-2968
Ruth Bowness2School of Medicine, University of St Andrews, North Haugh, St Andrews, UK.
Simon Dobson1School of Computer Science, University of St Andrews, North Haugh, St Andrews, UK.
Stephen H Gillespie2School of Medicine, University of St Andrews, North Haugh, St Andrews, UK.

Funding

Medical Research Council MR/P014704/1
6 · The paper itself

Abstract

Tuberculosis (TB) is an ancient disease that, although curable, still accounts for over 1 million deaths worldwide. Shortening treatment time is an important area of research but is hampered by the lack of models that mimic the full range of human pathology. TB shows distinct localisations during different stages of infection, the reasons for which are poorly understood. Greater understanding of how heterogeneity within the human lung influences disease progression may hold the key to improving treatment efficiency and reducing treatment times. In this work, we present a novel

Indexed as

Complex networksComputational biologyIn-host modellingMetapopulationSpatial heterogeneityTuberculosis

Identifiers

PMID30839831
PMCPMC6214320

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.