ArticleLight, science & applications2018
Add-on plasmonic patch as a universal fluorescence enhancer.
Article in Light, science & applications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Rapid, Tunable, and Scalable Patterning of Plasmonic Films for Biosensing Applications.ACS applied materials & interfaces · 2025Article
- From adhesion to biofilms formation and resilience: Exploring the impact of silver nanoparticles-based biomaterials onBiofilm · 2025Article
- Plasmonic biosensors and actuators for integrated point-of-care diagnostics.Npj biosensing · 2025Review
- Plasmonic nanoparticle sensors: current progress, challenges, and future prospects.Nanoscale horizons · 2024Review
- Fluorophore Interactions with the Surface Modes and Internal Modes of a Photonic Crystal.Optical Materials · 2024Article
- Plasmonic Fluorescence Enhancement in Diagnostics for Clinical Tests at Point-of-Care: A Review of Recent Technologies.Advanced materials (Deerfield Beach, Fla.) · 2023Review
- Bionic Plasmonic Nanoarrays Excited by Radially Polarized Vector Beam for Metal-Enhanced Fluorescence.Nanomaterials (Basel, Switzerland) · 2023Article
- Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications.Micromachines · 2023Review
- Quantitative and sensitive detection of alpha fetoprotein in serum by a plasmonic sensor.Nanophotonics (Berlin, Germany) · 2022Article
- High-resolution imaging of protein secretion at the single-cell level using plasmon-enhanced FluoroDOT assay.Cell reports methods · 2022Article
- Plasmonically-enhanced competitive assay for ultrasensitive and multiplexed detection of small molecules.Biosensors & bioelectronics · 2022Article
- Plasmonic nanosensors for point-of-care biomarker detection.Materials today. Bio · 2022Review
- Double-Resonant Nanostructured Gold Surface for Multiplexed Detection.ACS applied materials & interfaces · 2022Article
- Plasmonically Enhanced CRISPR/Cas13a-Based Bioassay for Amplification-Free Detection of Cancer-Associated RNA.Advanced healthcare materials · 2021Article
- Adiabatic mode transformation in width-graded nano-gratings enabling multiwavelength light localization.Scientific reports · 2021Article
- Ultrasensitive antibody-aptamer plasmonic biosensor for malaria biomarker detection in whole blood.Nature communications · 2020Article
- Recent Developments in Plasmonic Nanostructures for Metal Enhanced Fluorescence-Based Biosensing.Nanomaterials (Basel, Switzerland) · 2020Review
- PRADA: Portable Reusable Accurate Diagnostics with nanostar Antennas for multiplexed biomarker screening.Bioengineering & translational medicine · 2020Article
- Ultrabright Fluorescence Readout of an Inkjet-Printed Immunoassay Using Plasmonic Nanogap Cavities.Nano letters · 2020Article
- Ultrabright fluorescent nanoscale labels for the femtomolar detection of analytes with standard bioassays.Nature biomedical engineering · 2020Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Fluorescence-based techniques are the cornerstone of modern biomedical optics, with applications ranging from bioimaging at various scales (organelle to organism) to detection and quantification of a wide variety of biological species of interest. However, the weakness of the fluorescence signal remains a persistent challenge in meeting the ever-increasing demand to image, detect, and quantify biological species with low abundance. Here, we report a simple and universal method based on a flexible and conformal elastomeric film with adsorbed plasmonic nanostructures, which we term a "plasmonic patch," that provides large (up to 100-fold) and uniform fluorescence enhancement on a variety of surfaces through simple transfer of the plasmonic patch to the surface. We demonstrate the applications of the plasmonic patch in improving the sensitivity and limit of detection (by more than 100 times) of fluorescence-based immunoassays implemented in microtiter plates and in microarray format. The novel fluorescence enhancement approach presented here represents a disease, biomarker, and application agnostic ubiquitously applicable fundamental and enabling technology to immediately improve the sensitivity of existing analytical methodologies in an easy-to-handle and cost-effective manner, without changing the original procedures of the existing techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.