ArticleLight, science & applications2018
Phase-sensitive plasmonic biosensor using a portable and large field-of-view interferometric microarray imager.
Article in Light, science & applications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Nanophotonic sensing and label-free imaging of extracellular vesicles.Light, science & applications · 2025Review
- High-Sensitivity Goos-Hänchen Shift Sensing via Surface Plasmon Resonance and Beam Displacement Amplification.Sensors (Basel, Switzerland) · 2025Article
- MoSNanomaterials (Basel, Switzerland) · 2025Review
- Trapping light in air with membrane metasurfaces for vibrational strong coupling.Nature communications · 2024Article
- Nanoplasmonic biosensors for environmental sustainability and human health.Chemical Society reviews · 2024Review
- Imaging Diffractometric Biosensors for Label-Free, Multi-Molecular Interaction Analysis.Biosensors · 2024Article
- Multispectral Holographic Intensity and Phase Imaging of Semitransparent Ultrathin Films.ACS photonics · 2024Article
- Article
- Phase-driven progress in nanophotonic biosensing.Light, science & applications · 2024Article
- Emerging Multifunctional Carbon-Nanomaterial-Based Biosensors for Cancer Diagnosis.Small science · 2024Article
- Complex-frequency waves: beat loss and win sensitivity.Light, science & applications · 2024Article
- Label-free biosensing with singular-phase-enhanced lateral position shift based on atomically thin plasmonic nanomaterials.Light, science & applications · 2024Article
- Reviewing advances in nanophotonic biosensors.Frontiers in chemistry · 2024Review
- Topological Darkness: How to Design a Metamaterial for Optical Biosensing with Ultrahigh Sensitivity.ACS nano · 2023Article
- Recent Advances in Metaphotonic Biosensors.Biosensors · 2023Review
- A review of Optical Point-of-Care devices to Estimate the Technology Transfer of These Cutting-Edge Technologies.Biosensors · 2022Review
- Label-free optical biosensors in the pandemic era.Nanophotonics (Berlin, Germany) · 2022Review
- Surface plasmon resonance biosensor with laser heterodyne feedback for highly-sensitive and rapid detection of COVID-19 spike antigen.Biosensors & bioelectronics · 2022Article
- Multiplexed COVID-19 antibody quantification from human sera using label-free nanoplasmonic biosensors.Biomedical optics express · 2022Article
- Influence of Random Plasmonic Metasurfaces on Fluorescence Enhancement.Materials (Basel, Switzerland) · 2022Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanophotonics, and more specifically plasmonics, provides a rich toolbox for biomolecular sensing, since the engineered metasurfaces can enhance light-matter interactions to unprecedented levels. So far, biosensing associated with high-quality factor plasmonic resonances has almost exclusively relied on detection of spectral shifts and their associated intensity changes. However, the phase response of the plasmonic resonances have rarely been exploited, mainly because this requires a more sophisticated optical arrangement. Here we present a new phase-sensitive platform for high-throughput and label-free biosensing enhanced by plasmonics. It employs specifically designed Au nanohole arrays and a large field-of-view interferometric lens-free imaging reader operating in a collinear optical path configuration. This unique combination allows the detection of atomically thin (angstrom-level) topographical features over large areas, enabling simultaneous reading of thousands of microarray elements. As the plasmonic chips are fabricated using scalable techniques and the imaging reader is built with low-cost off-the-shelf consumer electronic and optical components, the proposed platform is ideal for point-of-care ultrasensitive biomarker detection from small sample volumes. Our research opens new horizons for on-site disease diagnostics and remote health monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.