Evidence map›Paper›PMID 30839045›Full record

ArticleChemical communications (Cambridge, England)2019

Red-emitting pyrene-benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect.

Chathura S Abeywickrama, Kaveesha J Wijesinghe, Robert V Stahelin, Yi Pang

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. A Modular Fluorescent Probe for Viscosity and Polarity Sensing in DNA Hybrid Mesostructures.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chathura S AbeywickramaDepartment of Chemistry, University of Akron, Akron, Ohio 44325, USA. yp5@uakron.edu.
Kaveesha J Wijesinghe
Robert V Stahelin
Yi Pang

Funding

Chemistry-Biochemistry-Biology Training Program at Notre DameT32GM075762 · NIGMS · UNIVERSITY OF NOTRE DAME · PI CHANG, MAYLAND F, MOBASHERY, SHAHRIAR · 2007 to 2021
$3.7M
NIR-Emitting Fluorescent Probes with Large Stokes Shift for Improved Zebrafish Neuromast ImagingR15GM126438 · NIGMS · UNIVERSITY OF AKRON · PI PANG, YI · 2018 to 2018
$417k
NIGMS NIH HHS R15 GM126438NIGMS NIH HHS T32 GM075762
6 · The paper itself

Abstract

A series of pyrene-benzothiazolium probes were synthesized. By replacing the pyridinium with a benzothiazolium unit, the selectivity of pyrene-derivatives is found to switch from nuclear to cellular lysosomes. New probes do not require proton participation and exhibit high biocompatibility and long-term imaging ability.

Indexed as

AnimalsBenzothiazolesCell LineChlorocebus aethiopsCOS CellsFluorescent DyesHumansLysosomesMicroscopy, ConfocalMicroscopy, FluorescenceOptical ImagingPyrenesBenzothiazolesFluorescent DyesPyrenes

Identifiers

PMID30839045
PMCPMC6446231

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.