ArticleAmerican journal of physiology. Lung cellular and molecular physiology2019
Surfactant plus budesonide decreases lung and systemic inflammation in mechanically ventilated preterm sheep.
Article in American journal of physiology. Lung cellular and molecular physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Surfactant-Budesonide Combination to Prevent Death or Bronchopulmonary Dysplasia: A Systematic Review and Meta-Analysis.Neonatology · 2026Pooled it
- Budesonide and hydrocortisone have differential effects on lung and brain in ventilated preterm lambs.Pediatric research · 2025Article
- Postnatal budesonide improved lung function in preterm lambs exposed to antenatal steroids and chorioamnionitis.Pediatric research · 2024Article
- Thermodynamic and Structural Study of Budesonide-Exogenous Lung Surfactant System.International journal of molecular sciences · 2024Article
- Efficacy of β2-adrenergic receptor agonist combined with corticosteroid in the treatment of children with cough variant asthma.World journal of clinical cases · 2023Article
- Preterm lung and brain responses to mechanical ventilation and corticosteroids.Journal of perinatology : official journal of the California Perinatal Association · 2023Review
- Preterm ovine respiratory epithelial cell responses to mechanical ventilation, lipopolysaccharide, and interleukin-13.American journal of physiology. Lung cellular and molecular physiology · 2023Article
- The Effect of Ipratropium Bromide with Violet Flower Extract, Ipratropium Bromide with Budesonide, and Ipratropium Bromide Alone on the Cuff-Leak of the Endotracheal Tube in Intubated ICU Patients.Advanced biomedical research · 2023Article
- The benefits, limitations and opportunities of preclinical models for neonatal drug development.Disease models & mechanisms · 2022Review
- Potential therapeutic role of budesonide to reduce COVID-19 severity.Journal of infection and public health · 2022Article
- The Change of Cytokines and Gut Microbiome in Preterm Infants for Bronchopulmonary Dysplasia.Frontiers in microbiology · 2022Article
- The International Week of Surfactant Research: Increasing knowledge about surfactant and unexploited opportunities.Biomedical journal · 2021Article
- Strategies to protect surfactant and enhance its activity.Biomedical journal · 2021Review
- Oxygen Toxicity to the Immature Lung-Part I: Pathomechanistic Understanding and Preclinical Perspectives.International journal of molecular sciences · 2021Review
- Intra-tracheal surfactant/budesonide versus surfactant alone: Comparison of two consecutive cohorts of extremely preterm infants.Pediatric pulmonology · 2021Article
- Surfactant-Assisted Distal Pulmonary Distribution of Budesonide Revealed by Mass Spectrometry Imaging.Pharmaceutics · 2021Article
- Aerosol drug delivery to spontaneously-breathing preterm neonates: lessons learned.Respiratory research · 2021Review
- Surfactant and budesonide for respiratory distress syndrome: an observational study.Pediatric research · 2020Observational
- Surfactant plus budesonide decreases lung and systemic responses to injurious ventilation in preterm sheep.American journal of physiology. Lung cellular and molecular physiology · 2020Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
Abstract
Mechanical ventilation with normal tidal volumes (V
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.