Evidence map›Paper›PMID 30838572›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2019

Bioengineering Tooth Bud Constructs Using GelMA Hydrogel.

Elizabeth E Smith, Pamela C Yelick

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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  3. Article
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  7. Review
  8. Tooth Bioengineering and Regenerative Dentistry.Journal of dental research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Elizabeth E SmithDepartment of Cell, Molecular, and Developmental Biology, Sackler School of Graduate Biomedical Sciences, Tufts University School Medicine, Boston, MA, USA.
Pamela C YelickDepartment of Orthodontics, Tufts University School of Dental Medicine, Boston, MA, USA. pamela.yelick@tufts.edu.

Funding

Dental Stem Cells and Tooth Tissue EngineeringR01DE016132 · NIDCR · TUFTS UNIVERSITY BOSTON · PI YELICK, PAMELA C · 2005 to 2014
$5.5M
Bioengineered Composite Alveolar Bone-Tooth Constructs for Tooth RegenerationR01DE026731 · NIDCR · TUFTS UNIVERSITY BOSTON · PI YELICK, PAMELA C · 2017 to 2021
$3.6M
Bioengineered 3D Tooth Constructs for Whole Tooth RegenerationF31DE026361 · NIDCR · TUFTS UNIVERSITY BOSTON · PI SMITH, ELIZABETH ERIN · 2016 to 2017
$76k
NIDCR NIH HHS F31 DE026361NIDCR NIH HHS R01 DE016132NIDCR NIH HHS R01 DE026731
6 · The paper itself

Abstract

Bioengineered dental tissues and whole teeth that exhibit features and properties of natural teeth can functionally surpass currently used artificial dental implants. However, no biologically based alternatives currently exist for clinical applications in dentistry. Here, we describe a newly established bioengineered tooth bud model for eventual applications in clinical dentistry. We also describe methods to fabricate and analyze bioengineered tooth tissues, including cell isolation, in vivo implantation, and post-harvest analyses.

Indexed as

Tissue ScaffoldsAnimalsCells, CulturedHydrogelsSwineTissue EngineeringToothHydrogelsHydrogel scaffoldsOdontogenesisPrimary dental cell cultureTooth tissue engineering

Identifiers

PMID30838572
PMCPMC6685533

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.