ArticleMovement disorders clinical practice
The Burke-Fahn-Marsden Dystonia Rating Scale is Age-Dependent in Healthy Children.
Article in Movement disorders clinical practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Magnetic Resonance Imaging and Its Clinical Correlation in Spinocerebellar Ataxia Type 3: A Systematic Review.Frontiers in neuroscience · 2022Pooled it
- Epidemiology of Pediatric Essential Tremor in the United States: A Systematic Literature Review from 2010 to 2020.Tremor and other hyperkinetic movements (New York, N.Y.) · 2022Pooled it
- The Brain-Age Gap in Pediatric Dystonia: Neuroanatomical Deviations Inform Deep Brain Stimulation Outcomes.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Dystonia Scales for Children: Challenges and Obstacles in DBS Practice.Movement disorders clinical practice · 2026Review
- Status dystonicus is a distinct state characterized by pallidal beta-band activity.Nature communications · 2025Article
- Efficacy of deep brain stimulation in treating monogenic dystonia symptoms: protocol for a systematic review.BMJ open · 2025Article
- Deep Brain Stimulation for Dystonia in the Netherlands: A Delphi Study to Develop National Consensus.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025Article
- Deep Brain Stimulation in Pediatric Populations: A Scoping Review of the Clinical Trial Landscape.Stereotactic and functional neurosurgery · 2025Article
- Pallidal and Thalamic Deep Brain Stimulation in the Treatment of Unilateral Dystonia: A Prospective Assessment.Movement disorders clinical practice · 2024Article
- Neurosurgical and pharmacological management of dystonia.World journal of psychiatry · 2024Review
- Severe Pediatric Dystonia Responding to Deep Brain Stimulation in 22q11.2 Microduplication Syndrome: Rare Clinical Presentation.Movement disorders clinical practice · 2024Article
- An Empirical Comparison of Commonly Used Universal Rating Scales for Dystonia.Movement disorders clinical practice · 2023Article
- Quantification of Behavioral Deficits in Developing Mice With Dystonic Behaviors.Dystonia (Lausanne, Switzerland) · 2022Article
- Early Onset Ataxia with Comorbid Dystonia: Clinical, Anatomical and Biological Pathway Analysis Expose Shared Pathophysiology.Diagnostics (Basel, Switzerland) · 2020Article
- The neurological phenotype of developmental motor patterns during early childhood.Brain and behavior · 2019Article
- Crossing barriers: a multidisciplinary approach to children and adults with young-onset movement disorders.Journal of clinical movement disorders · 2018Article
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Authors and funding
11 authors.
Funding
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Abstract
backgroundThe Burke-Fahn-Marsden Dystonia Rating Scale is a universally applied instrument for the quantitative assessment of dystonia in both children and adults. However, immature movements by healthy young children may also show "dystonic characteristics" as a consequence of physiologically incomplete brain maturation. This could implicate that Burke-Fahn-Marsden scale scores are confounded by pediatric age.
objectiveIn healthy young children, we aimed to determine whether physiologically immature movements and postures can induce an age-related effect on Burke-Fahn-Marsden movement and disability scale scores.
methodsNine assessors specializied in movement disorders (3 adult neurologists, 3 pediatric neurologists, and 3 MD/PhD students) independently scored the Burke-Fahn-Marsden movement scale in 52 healthy children (4-16 years of age; 2 boys and 2 girls per year of age). Independent of that, parents scored their children's functional motor development according to the Burke-Fahn-Marsden disability scale in another 52 healthy children (4-16 years of age; 2 boys and 2 girls per year of age). By regression analysis, we determined the association between Burke-Fahn-Marsden movement and disability scales outcomes and pediatric age.
resultsIn healthy children, assessment of physiologically immature motor performances by the Burke-Fahn-Marsden movement and disability scales showed an association between the outcomes of both scales and age (until 16 years and 12 years of age, β = -0.72 and β = -0.60, for Burke-Fahn-Marsden movement and disability scale, respectively [both
conclusionsThe Burke-Fahn-Marsden movement and disability scales are influenced by the age of the child. For accurate interpretation of longitudinal Burke-Fahn-Marsden Dystonia Rating Scale scores in young dystonic children, consideration of pediatric age-relatedness appears advisory.
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