Evidence map›Paper›PMID 30838173›Full record

ArticleFrontiers in oncology2019

An Efficacious Endometrial Sampler for Screening Endometrial Cancer.

Lu Han, Jiang Du, Lanbo Zhao, Chao Sun, Qi Wang, Xiaoqian Tuo, Huilian Hou, Yu Liu, Qing Wang, Qurat Ulain and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. HypermethylatedFrontiers in oncology · 2022
    Article
  9. Near-Infrared Fluorescent Agent forFrontiers in oncology · 2021
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Lu HanCenter for Single-Cell Biology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Jiang DuDepartment of Gynecology and Obstetrics, Shaanxi Provincial People's Hospital, Xi'an, China.
Lanbo ZhaoGuipei 77, Health Science Center, Xi'an Jiaotong University, Xi'an, China.
Chao SunCenter for Single-Cell Biology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Qi WangCenter for Single-Cell Biology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Xiaoqian TuoCenter for Single-Cell Biology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Huilian HouDepartment of Pathology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Yu LiuDepartment of Pathology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Qing WangCenter for Single-Cell Biology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Qurat UlainCenter for Single-Cell Biology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Shulan LvDepartment of Obstetrics and Gynecology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Guanjun ZhangDepartment of Pathology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Qing SongCenter for Single-Cell Biology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Qiling LiCenter for Single-Cell Biology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
First Affiliated Hospital of Xi'an Jiaotong University · CNShaanxi Provincial People's Hospital · CNXi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recently, the research on early detection of precancerous change and endometrial carcinoma has been focusing on minimally invasive procedures for screening. On this basis, we aim to verify the feasibility of endometrial samplers for screening endometrial cancer using Li Brush. We recruited patients undergoing hysterectomy for different diseases from the Inpatient Department of the Department of Obstetrics and Gynecology. Before surgery, endometrial cells were collected by Li Brush. The cytopathologic diagnosis from Li Brush and the histopathologic diagnosis from hysterectomy in the same patient were compared to calculate sensitivity (Se), specificity (Sp), false-negative rate (FNR), false-positive rate (FPR), positive predictive value (PV+) %, and negative predictive value (PV-). The research enrolled 293 women into this self-controlled trial. According to the hypothesis test of paired four lattices, we obtained the following indicators: Se 92.73, Sp 98.15, FNR 7.27, FPR 1.85, PV+92.73, and PV-98.15%. The endometrial sampler Li Brush is an efficacious instrument for screening endometrial cancer.

Indexed as

cytologyendometrial cancerendometrial samplerhistopathologyscreening

Identifiers

PMID30838173
PMCPMC6389657
OpenAlexW2916544716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.