Evidence map›Paper›PMID 30838002›Full record

ArticleFrontiers in immunology2019

Transcriptome Profiles of Human Visceral Adipocytes in Obesity and Colorectal Cancer Unravel the Effects of Body Mass Index and Polyunsaturated Fatty Acids on Genes and Biological Processes Related to Tumorigenesis.

Manuela Del Cornò, Antonella Baldassarre, Enrica Calura, Lucia Conti, Paolo Martini, Chiara Romualdi, Rosaria Varì, Beatrice Scazzocchio, Massimo D'Archivio, Andrea Masotti and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 57 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Manuela Del CornòCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.
Antonella BaldassarreResearch Laboratories, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Enrica CaluraDepartment of Biology, University of Padua, Padua, Italy.
Lucia ContiCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.
Paolo MartiniDepartment of Biology, University of Padua, Padua, Italy.
Chiara RomualdiDepartment of Biology, University of Padua, Padua, Italy.
Rosaria VarìCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.
Beatrice ScazzocchioCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.
Massimo D'ArchivioCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.
Andrea MasottiResearch Laboratories, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Sandra GessaniCenter for Gender-Specific Medicine, Istituto Superiore di Sanità, Rome, Italy.
Istituto Superiore di Sanità · ITUniversity of Padua · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity, a low-grade inflammatory condition, represents a major risk factor for the development of several pathologies including colorectal cancer (CRC). Although the adipose tissue inflammatory state is now recognized as a key player in obesity-associated morbidities, the underlying biological processes are complex and not yet precisely defined. To this end, we analyzed transcriptome profiles of human visceral adipocytes from lean and obese subjects affected or not by CRC by RNA sequencing (

Indexed as

AdipocytesAdipose TissueAdultAgedBiological PhenomenaBody Mass IndexCarcinogenesisColorectal NeoplasmsFatty Acids, Omega-3Fatty Acids, UnsaturatedFemaleHumansInflammationLipid MetabolismMaleMiddle AgedFatty Acids, Omega-3Fatty Acids, Unsaturatedadipocytebody mass indexcolorectal cancerfatty acidobesityRNASeqtranscriptome

Identifiers

PMID30838002
PMCPMC6389660
OpenAlexW2911791160

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.