Evidence map›Paper›PMID 30838000›Full record

ArticleFrontiers in immunology2019

Circulating Mucosal-Associated Invariant T Cells in a Large Cohort of Healthy Chinese Individuals From Newborn to Elderly.

Pengcheng Chen, Wenhai Deng, Dandan Li, Tai Zeng, Ling Huang, Qun Wang, Jinli Wang, Weiguang Zhang, Xiaoxiao Yu, Deming Duan and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 58 citations in OpenAlex.

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  11. Diverging patterns in innate immunity against respiratory viruses during a lifetime: lessons from the young and the old.European respiratory review : an official journal of the European Respiratory Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 3 countries.

Pengcheng ChenZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Wenhai DengZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Dandan LiZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Tai ZengZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Ling HuangZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Qun WangZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Jinli WangZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Weiguang ZhangZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Xiaoxiao YuZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Deming DuanZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Jinle WangSecond Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University Wenzhou, China.
Hong XiaFirst Affiliated Hospital of Wenzhou Medical University Wenzhou, China.
Hanbin ChenFirst Affiliated Hospital of Wenzhou Medical University Wenzhou, China.
Wesley HuangSan Marino High School, San Marino, CA, United States.
Jingao LiDepartment of Radiation Oncology, Jiangxi Cancer Hospital, Nanchang, China.
Dahong ZhangDepartment of Urology, Zhejiang Provincial People's Hospital, Hangzhou, China.
Xiao-Ping ZhongZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Jimin GaoZhejiang Provincial Key Lab for Technology and Application of Model Organisms, School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, China.
Wenzhou Medical University · CNFirst Affiliated Hospital of Wenzhou Medical University · CNJiangxi Provincial Cancer Hospital · CNSecond Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University · CNUniversity of the Republic of San Marino · SMZhejiang Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosal-associated invariant T (MAIT) cells, which are enriched in human blood and express a semi-invariant TCR chain, play important roles in conditions such as infectious diseases and cancer. The influence of age on levels and functional characteristics of circulating MAIT cells have not been fully addressed. Here we have collected blood samples from a large cohort of healthy Chinese individuals from newborn (cord blood) to the elderly and assessed the levels of circulating MAIT cells as well as their phenotype, activation and apoptosis status, and cytokine expression profiles after

Indexed as

AdultAgedAsian PeopleChild, PreschoolCohort StudiesCytokinesFemaleHumansInfant, NewbornInterleukin-17Lymphocyte ActivationMaleMiddle AgedMucosal-Associated Invariant T CellsReceptors, CCRCytokinesInterleukin-17Receptors, CCRactivationagehealthy Chinese cohortmucosal-associated invariant T cellphenotype

Identifiers

PMID30838000
PMCPMC6389679
OpenAlexW2916028407

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.