Evidence map›Paper›PMID 30837954›Full record

ArticleFrontiers in endocrinology2019

Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T

Leonardo Lorenzini, Nhat Minh Nguyen, Ginevra Sacripanti, Enrico Serni, Marco Borsò, Federica Saponaro, Elena Cecchi, Tommaso Simoncini, Sandra Ghelardoni, Riccardo Zucchi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. The role of thyroid hormone in metabolism and metabolic syndrome.Therapeutic advances in endocrinology and metabolism · 2020
    Review
  10. Novel thyroid hormones.Endocrine · 2019
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Leonardo LorenziniDepartment of Pathology, University of Pisa, Pisa, Italy.
Nhat Minh NguyenDepartment of Pathology, University of Pisa, Pisa, Italy.
Ginevra SacripantiDepartment of Pathology, University of Pisa, Pisa, Italy.
Enrico SerniDepartment of Pathology, University of Pisa, Pisa, Italy.
Marco BorsòDepartment of Pathology, University of Pisa, Pisa, Italy.
Federica SaponaroDepartment of Pathology, University of Pisa, Pisa, Italy.
Elena CecchiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Tommaso SimonciniDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Sandra GhelardoniDepartment of Pathology, University of Pisa, Pisa, Italy.
Riccardo ZucchiDepartment of Pathology, University of Pisa, Pisa, Italy.
Alessandro SabaDepartment of Pathology, University of Pisa, Pisa, Italy.
University of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

3,5-diiodo-L-thyronine (3,5-T2) is an endogenous derivative of thyroid hormone with potential metabolic effects. It has been detected in human blood by immunological methods, but a reliable assay based on mass spectrometry (MS), which is now regarded as the gold standard in clinical chemistry, is not available yet. Therefore, we aimed at developing a novel

Indexed as

3, 5-diiodo-L-thyroninemass spectrometryT2thyroid hormonesthyroid hormones metabolites

Identifiers

PMID30837954
PMCPMC6389606
OpenAlexW2917149508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.