Evidence map›Paper›PMID 30837887›Full record

SynthesisFrontiers in physiology2019

Meta-Analysis of Risk Stratification of SCN5A With Brugada Syndrome: Is SCN5A Always a Marker of Low Risk?

Yihan Yang, Dan Hu, Frederic Sacher, Kengo F Kusano, Xinye Li, Hector Barajas-Martinez, Mélèze Hocini, Yanda Li, Yonghong Gao, Hongcai Shang and 1 more

Open access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. The SCN5A Gene Is a Predictor of Phenotype Severity in Brugada Syndrome: A Comprehensive Literature Review.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2023
    Pooled it
  2. Article
  3. Article
  4. Review
  5. European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the state of genetic testing for cardiac diseases.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Catheter ablation in highly symptomatic Brugada patients: a Dutch case series.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
    Article
  10. Brugada Syndrome: Oligogenic or Mendelian Disease?International journal of molecular sciences · 2020
    Review
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Yihan YangGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, China.
Dan HuDepartment of Cardiology and Cardiovascular Research Institution, Renmin Hospital of Wuhan University, Wuhan, China.
Frederic SacherHôpital Cardiologique Haut Lévêque, Lyric institute, Université de Bordeaux, Bordeaux-Pessac, France.
Kengo F KusanoDivision of Arrhythmia and Electrophysiology, Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Xinye LiGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, China.
Hector Barajas-MartinezGlobal Genetics Corp, Ventura, CA, United States.
Mélèze HociniHôpital Cardiologique Haut Lévêque, Lyric institute, Université de Bordeaux, Bordeaux-Pessac, France.
Yanda LiGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, China.
Yonghong GaoKey Laboratory of Chinese Internal Medicine of the Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China.
Hongcai ShangKey Laboratory of Chinese Internal Medicine of the Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China.
Yanwei XingGuang'anmen Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNDongzhimen Hospital Affiliated to Beijing University of Chinese Medicine · CNGuang’anmen Hospital · CNHôpital Cardiologique du Haut-Lévêque · FRNational Cerebral and Cardiovascular Center · JPRenmin Hospital of Wuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

arrhythmiabrugada syndromeelectrophysiology studySCN5Asudden cardiac death

Identifiers

PMID30837887
PMCPMC6389868
OpenAlexW2917182899

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.