Evidence map›Paper›PMID 30837881›Full record

ArticleFrontiers in pharmacology2019

Identification of Biologically Active

Michelle M Martínez-Montemayor, Taotao Ling, Ivette J Suárez-Arroyo, Gabriela Ortiz-Soto, Camille L Santiago-Negrón, Mercedes Y Lacourt-Ventura, Anibal Valentín-Acevedo, Walter H Lang, Fatima Rivas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it, 99 citations in OpenAlex.

  1. Use ofNutrients · 2020
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Effect ofFood science & nutrition · 2025
    Article
  7. Article
  8. Potential Active Compounds ofFood science & nutrition · 2025
    Review
  9. Article
  10. Antioxidants (Basel, Switzerland) · 2025
    Article
  11. Unlocking the Potential ofPharmaceutics · 2025
    Review
  12. Review
  13. Review
  14. Hypoglycemic Properties ofJournal of fungi (Basel, Switzerland) · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. A Phyto-mycotherapeutic Supplement, NamelyInternational journal of molecular sciences · 2024
    Article
  19. Bioactivity Profiling ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  20. Comprehensive Analysis of Bioactive Compounds in WildPharmaceuticals (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Michelle M Martínez-MontemayorCancer Research Unit, Department of Biochemistry, School of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico.
Taotao LingDepartment of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, United States.
Ivette J Suárez-ArroyoCancer Research Unit, Department of Biochemistry, School of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico.
Gabriela Ortiz-SotoCancer Research Unit, Department of Biochemistry, School of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico.
Camille L Santiago-NegrónDepartment of Biology, University of Puerto Rico, Bayamón, Puerto Rico.
Mercedes Y Lacourt-VenturaCancer Research Unit, Department of Biochemistry, School of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico.
Anibal Valentín-AcevedoDepartment of Microbiology and Immunology, School of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico.
Walter H LangDepartment of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, United States.
Fatima RivasDepartment of Chemical Biology & Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, United States.
Central University of the Caribbean · PRSt. Jude Children's Research Hospital · USUniversity of Puerto Rico at Bayamón · PR

Funding

UNIVERSITY MEDICAL RESEARCH CENTERG12RR003035 · NCRR · UNIVERSIDAD CENTRAL DEL CARIBE · PI ROJAS, LEGIER V · 1986 to 2011
$26.7M
UNIVERSIDAD CENTRAL DEL CARIBE BIOMEDICAL RESEARCH CENTERSG12MD007583 · NIMHD · UNIVERSIDAD CENTRAL DEL CARIBE · PI RODRIGUEZ, JOSE GINEL · 2012 to 2016
$8.4M
Sensitization of breast cancer and cancer stem cell to systemic therapy by ReishiSC3GM111171 · NIGMS · UNIVERSIDAD CENTRAL DEL CARIBE · PI MARTINEZ, MICHELLE M · 2014 to 2019
$461k
NCRR NIH HHS G12 RR003035NIGMS NIH HHS SC3 GM111171NIMHD NIH HHS G12 MD007583
6 · The paper itself

Abstract

We previously reported that

Indexed as

breast cancerEP derivativesergosterol peroxideGanoderma lucidumnatural product

Identifiers

PMID30837881
PMCPMC6389703
OpenAlexW2917679048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.