ArticleFrontiers in aging neuroscience2019
Aging and Hypertension - Independent or Intertwined White Matter Impairing Factors? Insights From the Quantitative Diffusion Tensor Imaging.
Article in Frontiers in aging neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- Alterations of White Matter Connectivity in Adults with Essential Hypertension.International journal of general medicine · 2024Trial
- Association of Intensive vs Standard Blood Pressure Control With Regional Changes in Cerebral Small Vessel Disease Biomarkers: Post Hoc Secondary Analysis of the SPRINT MIND Randomized Clinical Trial.JAMA network open · 2023Trial
- Genetically predicted white matter microstructure mediates the relationship between risk factors and lacunar stroke.Stroke and vascular neurology · 2026Article
- Investigating the association between human brainstem microstructural integrity and hypertension using magnetic resonance relaxometry.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Effects of hypertension and aging on brain function in spontaneously hypertensive rats: a longitudinal resting-state functional magnetic resonance imaging study.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Absence of fluctuation and inverted circadian rhythm of blood pressure increase the risk of cognitive dysfunction in cerebral small vessel disease patients.BMC neurology · 2023Article
- Different patterns of white matter lesions among patent foramen ovale, atherosclerotic cerebral small vessel disease and cerebral venous thrombosis.Journal of thrombosis and thrombolysis · 2022Article
- Age-related changes in cerebrovascular health and their effects on neural function and cognition: A comprehensive review.Psychophysiology · 2021Review
- Comparing the Performance of Two Radiomic Models to Predict Progression and Progression Speed of White Matter Hyperintensities.Frontiers in neuroinformatics · 2021Article
- Evolution of Brain Morphology in Spontaneously Hypertensive and Wistar-Kyoto Rats From Early Adulthood to Aging: A Longitudinal Magnetic Resonance Imaging Study.Frontiers in aging neuroscience · 2021Article
- Common Brain Structural Alterations Associated with Cardiovascular Disease Risk Factors and Alzheimer's Dementia: Future Directions and Implications.Neuropsychology review · 2020Review
- Associations between modifiable risk factors and white matter of the aging brain: insights from diffusion tensor imaging studies.Neurobiology of aging · 2019Review
- Risk factors and cognitive correlates of white matter hyperintensities in ethnically diverse populations without dementia: The COSMIC consortium.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging disrupts white matter integrity, and so does continuous elevated blood pressure that accompanies hypertension (HTN). Yet, our understanding of the interrelationship between these factors is still limited. The study aimed at evaluating patterns of changes in diffusion parameters (as assessed by quantitative diffusion fiber tracking - qDTI) following both aging, and hypertension, as well as the nature of their linkage. 146 participants took part in the study: the control group (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.