ArticleFrontiers in neuroscience2019
Preliminary Neurophysiological Evidence of Altered Cortical Activity and Connectivity With Neurologic Music Therapy in Parkinson's Disease.
Article in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Training Involving Rhythmic Auditory Stimulation on Upper-limb Movements in Patients With Parkinson's Disease
Effects and Neural Mechanisms of Training Involving Rhythmic Auditory Stimulation on Upper-limb Movements in Patients With Parkinson's Disease
Who cites it
21 citing papers in PubMed, 38 citations in OpenAlex.
- A Randomized Controlled Trial of Dual Upper-Extremity Training [DUET]: Combining Neurologic Music Therapy® with Noninvasive Brain Stimulation for Upper-Limb Performance in Corticobasal Syndrome.Movement disorders clinical practice · 2026Article
- Article
- Article
- A review of concurrent sonified biofeedback in balance and gait training.Journal of neuroengineering and rehabilitation · 2025Review
- A Cross-over Pilot Study on the Effects of Classical Guitar Instruction on Motor and Non-Motor Symptoms in People with Parkinson's Disease.Neuroscience insights · 2025Article
- Rhythms of relief: perspectives on neurocognitive mechanisms of music interventions in ADHD.Frontiers in psychology · 2025Article
- Effectiveness of music-based interventions for cognitive rehabilitation in Parkinson's disease: a systematic review of randomized controlled clinical trials.Psicologia, reflexao e critica : revista semestral do Departamento de Psicologia da UFRGS · 2023Review
- Article
- Music Therapy for Gait and Speech Deficits in Parkinson's Disease: A Mini-Review.Brain sciences · 2023Review
- Neurologic Music Therapy in Geriatric Rehabilitation: A Systematic Review.Healthcare (Basel, Switzerland) · 2022Review
- Finger dexterity measured by the Grooved Pegboard test indexes Parkinson's motor severity in a tremor-independent manner.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2022Article
- Research Progress of Music Therapy on Gait Intervention in Patients with Parkinson's Disease.International journal of environmental research and public health · 2022Review
- The Effect of Music-Based Rhythmic Auditory Stimulation on Balance and Functional Outcomes after Stroke.Healthcare (Basel, Switzerland) · 2022Article
- Dual-task walking improvement with enhanced kinesthetic awareness in Parkinson's disease with mild gait impairment: EEG connectivity and clinical implication.Frontiers in aging neuroscience · 2022Article
- GuitarPD: A Randomized Pilot Study on the Impact of Nontraditional Guitar Instruction on Functional Movement and Well-Being in Parkinson's Disease.Parkinson's disease · 2022Article
- Rhythm and Music-Based Interventions in Motor Rehabilitation: Current Evidence and Future Perspectives.Frontiers in human neuroscience · 2021Review
- Effective Connectivity During Rest and Music Listening: An EEG Study on Parkinson's Disease.Frontiers in aging neuroscience · 2021Article
- Neural plasticity: The substratum of music-based interventions in neurorehabilitation.NeuroRehabilitation · 2021Review
- An Overview of Acoustic-Based Interventions to Improve Motor Symptoms in Parkinson's Disease.Frontiers in aging neuroscience · 2020Review
- Music Therapy and Music-Based Interventions for Movement Disorders.Current neurology and neuroscience reports · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Neurologic Music Therapy (NMT) is a novel impairment-focused behavioral intervention system whose techniques are based on the clinical neuroscience of music perception, cognition, and production. Auditory Stimulation (RAS) is one of the NMT techniques, which aims to develop and maintain a physiological rhythmic motor activity through rhythmic auditory cues. In a series of breakthrough studies beginning in the mid-nineties, we discovered that RAS durably improves gait velocity, stride length, and cadence in Parkinson's disease (PD). No study to date reports the neurophysiological evidence of auditory-motor frequency entrainment after a NMT intervention in the Parkinson's community. We hypothesized that NMT-related motor improvements in PD are due to entrainment-related coupling between auditory and motor activity resulting from an increased functional communication between the auditory and the motor cortices. Spectral analysis in the primary motor and auditory cortices during a cued finger tapping task showed a simultaneous increase in evoked power in the beta-range along with an increased functional connectivity after a course of NMT in a small sample of three older adults with PD. This case study provides preliminary evidence that NMT-based motor rehabilitation may enhance cortical activation in the auditory and motor areas in a synergic manner. With a lack of both control subjects and control conditions, this neuroimaging case-proof of concept series of visible changes suggests potential mechanisms and offers further education on the clinical applications of musical interventions for motor impairments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.