Evidence map›Paper›PMID 30837680›Full record

ArticleBritish journal of cancer2019

The impact of psychiatric utilisation prior to cancer diagnosis on survival of solid organ malignancies.

Zachary Klaassen, Christopher J D Wallis, Hanan Goldberg, Thenappan Chandrasekar, Rashid K Sayyid, Stephen B Williams, Kelvin A Moses, Martha K Terris, Robert K Nam, David Urbach and 3 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06858202 (Structured Post-Operative Pain and Distress Treatment Intervention for Patients Undergoing Surgery for Intra-Abdominal Malignancies), which is not on this map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06858202 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Structured Post-Operative Pain and Distress Treatment Intervention for Patients Undergoing Surgery for Intra-Abdominal Malignancies

TypeinterventionalSponsorUniversity of UtahRan2025 to 2026Enrolled95ConditionsPsychological Distress, Intra-abdominal CancerArmsMindfulness Intervention, Non-mindfulness Intervention
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  12. Analysis of the influential factors of the emotional health of patients with cancer based on the structural equation model: the role of social media and emotional support.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  20. Mental Health in Urologic Oncology.Health psychology research · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Zachary KlaassenDepartment of Surgery, Division of Urology, University of Toronto, University Health Network, Princess Margaret Cancer Centre, Toronto, ON, Canada.
Christopher J D WallisDepartment of Surgery, Division of Urology, University of Toronto, University Health Network, Princess Margaret Cancer Centre, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-5990-4026
Hanan GoldbergDepartment of Surgery, Division of Urology, University of Toronto, University Health Network, Princess Margaret Cancer Centre, Toronto, ON, Canada.
Thenappan ChandrasekarDepartment of Surgery, Division of Urology, University of Toronto, University Health Network, Princess Margaret Cancer Centre, Toronto, ON, Canada.
Rashid K SayyidDivision of Urology, Medical College of Georgia-Augusta University, Augusta, GA, USA.
Stephen B WilliamsDivision of Urology, The University of Texas Medical Branch at Galveston, Galveston, TX, USA.
Kelvin A MosesDepartment of Urological Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Martha K TerrisDivision of Urology, Medical College of Georgia-Augusta University, Augusta, GA, USA.
Robert K NamInstitute for Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.
David UrbachInstitute for Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.
Peter C AustinInstitute for Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.
Paul KurdyakInstitute for Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada.
Girish S KulkarniDepartment of Surgery, Division of Urology, University of Toronto, University Health Network, Princess Margaret Cancer Centre, Toronto, ON, Canada. girish.kulkarni@uhn.ca.

Funding

Vanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9M
NCI NIH HHS K12 CA090625
6 · The paper itself

Abstract

backgroundAmong patients with cancer, prior research suggests that patients with mental illness may have reduced survival. The objective was to assess the impact of psychiatric utilisation (PU) prior to cancer diagnosis on survival outcomes.

methodsAll residents of Ontario diagnosed with one of the top 10 malignancies (1997-2014) were included. The primary exposure was psychiatric utilisation gradient (PUG) score in 5 years prior to cancer: 0: none, 1: outpatient, 2: emergency department, 3: hospital admission. A multivariable, cause-specific hazard model was used to assess the effect of PUG score on cancer-specific mortality (CSM), and a Cox proportional hazard model for effect on all-cause mortality (ACM).

resultsA toal of 676,125 patients were included: 359,465 (53.2%) with PUG 0, 304,559 (45.0%) PUG 1, 7901 (1.2%) PUG 2, and 4200 (0.6%) PUG 3. Increasing PUG score was independently associated with worse CSM, with an effect gradient across the intensity of pre-diagnosis PU (vs PUG 0): PUG 1 h 1.05 (95% CI 1.04-1.06), PUG 2 h 1.36 (95% CI 1.30-1.42), and PUG 3 h 1.73 (95% CI 1.63-1.84). Increasing PUG score was also associated with worse ACM.

conclusionsPre-cancer diagnosis PU is independently associated with worse CSM and ACM following diagnosis among patients with solid organ malignancies.

Indexed as

AgedCanadaDisease-Free SurvivalFemaleHumansMaleMental DisordersMiddle AgedNeoplasmsProportional Hazards Models

Identifiers

PMID30837680
PMCPMC6474265

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.