ArticleScientific reports2019
Simulation of blast lung injury induced by shock waves of five distances based on finite element modeling of a three-dimensional rat.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.
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6 citing papers in PubMed, 44 citations in OpenAlex.
- Assessment model of blast injury: A narrative review.iScience · 2025Review
- Magnetic Resonance Elastography and Computational Modeling Identify Heterogeneous Lung Biomechanical Properties during Cystic Fibrosis.Research square · 2024Article
- Article
- Identification of potentially functional circRNAs and prediction of the circRNA-miRNA-hub gene network in mice with primary blast lung injury.BMC pulmonary medicine · 2023Article
- Effects of orientation and distance of goats on blast lung injury characteristics on a plateau above 4500-meter.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2023Article
- Global gene expression profiling of blast lung injury of goats exposed to shock wave.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blast lung injury (BLI) caused by both military and civilian explosions has become the main cause of death for blast injury patients. By building three-dimensional (3D) models of rat explosion regions, we simulated the surface pressure of the skin and lung. The pressure distributions were performed at 5 distances from the detonation center to the center of the rat. When the distances were 40 cm, 50 cm, 60 cm, 70 cm and 80 cm, the maximum pressure of the body surface were 634.77kPa, 362.46kPa, 248.11kPa, 182.13kPa and 109.29kPa and the surfaces lung pressure ranges were 928-2916 Pa, 733-2254 Pa, 488-1236 Pa, 357-1189 Pa and 314-992 Pa. After setting 6 virtual points placed on the surface of each lung lobe model, simulated pressure measurement and corresponding pathological autopsies were then conducted to validate the accuracy of the modeling. For the both sides of the lung, when the distance were 40 cm, 50 cm and 60 cm, the Pearson's values showed strong correlations. When the distances were 70 cm and 80 cm, the Pearson's values showed weak linear correlations. This computational simulation provided dynamic anatomy as well as functional and biomechanical information.
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