ArticleNature communications2019
The Wolbachia mobilome in Culex pipiens includes a putative plasmid.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genomic evolution and adaptation of arthropod-associated Rickettsia.Scientific reports · 2022Pooled it
- Calibrating and documenting host-switching and evolution of incompatibility loci for two closely related Wolbachia clades.Genetics · 2026Article
- Genomic islands in Wolbachia prophages drive amplification and diversification of cytoplasmic incompatibility genes in Culex pipiens.Genetics · 2026Article
- Extensive mobilome dynamics in a widespread endosymbiont: long read metagenomics reveal dimeric plasmids and highly fragmented prophages in Wolbachia from Culex pipiens.Research square · 2026Article
- Calibrating and documenting host-switching and evolution of incompatibility loci for two closely relatedbioRxiv : the preprint server for biology · 2026Article
- Review
- Review
- Review
- Article
- Lack of abundant core virome inmSystems · 2024Article
- Diverse plasmid systems and their ecology across human gut metagenomes revealed by PlasX and MobMess.Nature microbiology · 2024Article
- Wolbachia: Advancing into a Second Century.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Article
- Intrinsic factors driving mosquito vector competence and viral evolution: a review.Frontiers in cellular and infection microbiology · 2023Review
- Genome sequencing and comparative analysis of Wolbachia strain wAlbA reveals Wolbachia-associated plasmids are common.PLoS genetics · 2022Article
- High molecular weight DNA extraction strategies for long-read sequencing of complex metagenomes.Molecular ecology resources · 2022Article
- Widespread phages of endosymbionts: Phage WO genomics and the proposed taxonomic classification of Symbioviridae.PLoS genetics · 2022Article
- Overview of paratransgenesis as a strategy to control pathogen transmission by insect vectors.Parasites & vectors · 2022Review
- Diversity and function of arthropod endosymbiont toxins.Trends in microbiology · 2022Review
- Positive Selection and Horizontal Gene Transfer in the Genome of a Male-Killing Wolbachia.Molecular biology and evolution · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
Abstract
Wolbachia is a genus of obligate intracellular bacteria found in nematodes and arthropods worldwide, including insect vectors that transmit dengue, West Nile, and Zika viruses. Wolbachia's unique ability to alter host reproductive behavior through its temperate bacteriophage WO has enabled the development of new vector control strategies. However, our understanding of Wolbachia's mobilome beyond its bacteriophages is incomplete. Here, we reconstruct near-complete Wolbachia genomes from individual ovary metagenomes of four wild Culex pipiens mosquitoes captured in France. In addition to viral genes missing from the Wolbachia reference genome, we identify a putative plasmid (pWCP), consisting of a 9.23-kbp circular element with 14 genes. We validate its presence in additional Culex pipiens mosquitoes using PCR, long-read sequencing, and screening of existing metagenomes. The discovery of this previously unrecognized extrachromosomal element opens additional possibilities for genetic manipulation of Wolbachia.
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