Evidence map›Paper›PMID 30837343›Full record

ArticlemBio2019

Distinct Physiological Roles of the Three Ferredoxins Encoded in the Hyperthermophilic Archaeon

Brett W Burkhart, Hallie P Febvre, Thomas J Santangelo

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

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  13. Review
  14. Article
  15. Diversification of Ferredoxins across Living Organisms.Current issues in molecular biology · 2021
    Article
  16. Article
  17. The Journal of biological chemistry · 2020
    Article
  18. Article
  19. Microbe Profile:Microbiology (Reading, England) · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brett W BurkhartDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, USA.
Hallie P FebvreDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, USA.
Thomas J SantangeloDepartment of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado, USA thomas.santangelo@colostate.edu.
Colorado State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Control of electron flux is critical in both natural and bioengineered systems to maximize energy gains. Both small molecules and proteins shuttle high-energy, low-potential electrons liberated during catabolism through diverse metabolic landscapes. Ferredoxin (Fd) proteins-an abundant class of Fe-S-containing small proteins-are essential in many species for energy conservation and ATP production strategies. It remains difficult to model electron flow through complicated metabolisms and in systems in which multiple Fd proteins are present. The overlap of activity and/or limitations of electron flux through each Fd can limit physiology and metabolic engineering strategies. Here we establish the interplay, reactivity, and physiological role(s) of the three ferredoxin proteins in the model hyperthermophile

Indexed as

Electron TransportEnergy MetabolismAdenosine TriphosphateFerredoxinsGene Expression Regulation, ArchaealThermococcusAdenosine TriphosphateFerredoxinsarchaeaelectron fluxferredoxinhydrogenasehyperthermophileThermococcus kodakarensis

Identifiers

PMID30837343
PMCPMC6401487
OpenAlexW2920788159

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.