Evidence map›Paper›PMID 30837316›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Temperature- and rigidity-mediated rapid transport of lipid nanovesicles in hydrogels.

Miaorong Yu, Wenyi Song, Falin Tian, Zhuo Dai, Quanlei Zhu, Ejaj Ahmad, Shiyan Guo, Chunliu Zhu, Haijun Zhong, Yongchun Yuan and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 139 citations in OpenAlex.

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  12. Microfluidic fabrication of pectin-coated liposomes for drug delivery.Drug delivery and translational research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Miaorong YuShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Wenyi SongShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Falin TianLaboratory of Theoretical and Computational Nanoscience, Chinese Academy of Sciences (CAS) Key Laboratory for Nanosystem and Hierarchy Fabrication, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, Chinese Academy of Sciences, 100190, Beijing, China.
Zhuo DaiShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Quanlei ZhuShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Ejaj AhmadShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Shiyan GuoShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Chunliu ZhuShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
Haijun ZhongDepartment of Pharmacy, Medical College of Nanchang University, Nanchang 330066, China.
Yongchun YuanShanghai Institute of Technical Physics, Chinese Academy of Sciences, Shanghai 200083, China.
Tao ZhangShanghai Institute of Technical Physics, Chinese Academy of Sciences, Shanghai 200083, China.
Xin YiDepartment of Mechanics and Engineering Science, College of Engineering, Beijing Innovation Center for Engineering Science and Advanced Technology, Peking University, Beijing 100871, China.
Xinghua ShiUniversity of Chinese Academy of Sciences, Beijing 100049, China; shixh@nanoctr.cn ygan@simm.ac.cn huajian_gao@brown.edu.ORCID 0000-0001-5012-3453
Yong GanShanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; shixh@nanoctr.cn ygan@simm.ac.cn huajian_gao@brown.edu.
Huajian GaoSchool of Engineering, Brown University, Providence, RI 02912 shixh@nanoctr.cn ygan@simm.ac.cn huajian_gao@brown.edu.ORCID 0000-0002-8656-846X
Chinese Academy of Sciences · CNBrown University · USNanchang University · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid nanovesicles are widely present as transport vehicles in living organisms and can serve as efficient drug delivery vectors. It is known that the size and surface charge of nanovesicles can affect their diffusion behaviors in biological hydrogels such as mucus. However, how temperature effects, including those of both ambient temperature and phase transition temperature (

Indexed as

AnimalsBiological TransportDiabetes Mellitus, ExperimentalDiffusionDrug CarriersDrug Delivery SystemsEpitheliumHydrogelsInsulinLipidsLiposomesMaleNanoparticlesPhase TransitionRatsRats, Sprague-DawleyDrug CarriersHydrogelsInsulinLipidsLiposomesbiological hydrogelsdiffusionlipid nanovesicleliposomephase transition temperature

Identifiers

PMID30837316
PMCPMC6431219
OpenAlexW2918343288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.