Evidence map›Paper›PMID 30837287›Full record

ArticleJournal of cell science2019

Juan Tao, Dinara Bulgari, Drew A Berkhoudt, Michael J Calderon, Simon C Watkins, Hector J Fonseca Velez, Nadezhda Sabeva, David L Deitcher, Edwin S Levitan

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Octopaminergic neurons have multiple targets inLearning & memory (Cold Spring Harbor, N.Y.) · 2021
    Article
  3. Vesicular neurotransmitter transporters in Drosophila melanogaster.Biochimica et biophysica acta. Biomembranes · 2020
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Juan TaoDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Dinara BulgariDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Drew A BerkhoudtDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Michael J CalderonDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Simon C WatkinsDepartment of Cell Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Hector J Fonseca VelezDepartment of Neuroscience, Universidad Central del Caribe, Bayamón, Puerto Rico 00960, USA.ORCID 0000-0002-5159-0755
Nadezhda SabevaDepartment of Neuroscience, Universidad Central del Caribe, Bayamón, Puerto Rico 00960, USA.ORCID 0000-0002-7714-4884
David L DeitcherDepartment of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA.
Edwin S LevitanDepartment of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA elevitan@pitt.edu.ORCID 0000-0003-3319-1344
University of Pittsburgh · USCentral University of the Caribbean · PRCornell University · US

Funding

Dense-Core Vesicle Circulation, Capture and Synaptic Neuropeptide ReleaseR01NS032385 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI EDWIN S LEVITAN · 1995 to 2026
$13.0M
Request for a Leica 3X STED MicroscopeS10OD021540 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WATKINS, SIMON C · 2016 to 2016
$1.2M
NIH HHS S10 OD021540NINDS NIH HHS R01 NS032385
6 · The paper itself

Abstract

Many neurons influence their targets through co-release of neuropeptides and small-molecule transmitters. Neuropeptides are packaged into dense-core vesicles (DCVs) in the soma and then transported to synapses, while small-molecule transmitters such as monoamines are packaged by vesicular transporters that function at synapses. These separate packaging mechanisms point to activity, by inducing co-release as the sole scaler of co-transmission. Based on screening in

Indexed as

AnimalsAxonsDrosophilaDrosophila ProteinsFemaleGene Expression Regulation, DevelopmentalMaleNeuronsNeuropeptidesReceptor-Like Protein Tyrosine Phosphatases, Class 4Secretory VesiclesSynapsesSynaptic VesiclesTransport VesiclesDrosophila ProteinsNeuropeptidesPtp4E protein, DrosophilaReceptor-Like Protein Tyrosine Phosphatases, Class 4Neuropeptide vesiclesSecretory granulesSynaptic transmissionTyrosine phosphataseVesicular transport

Identifiers

PMID30837287
PMCPMC6467486
OpenAlexW2919116071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.