Evidence map›Paper›PMID 30837265›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

GIRK Channel Activity in Dopamine Neurons of the Ventral Tegmental Area Bidirectionally Regulates Behavioral Sensitivity to Cocaine.

Nora M McCall, Ezequiel Marron Fernandez de Velasco, Kevin Wickman

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. NAcLat-DBS reduces GABANeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Frontiers in cellular neuroscience · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Neuronal G protein-gated KAmerican journal of physiology. Cell physiology · 2022
    Review
  14. Article
  15. Article
  16. A Brief History and the Significance of the GABACurrent topics in behavioral neurosciences · 2022
    Article
  17. Article
  18. Advances in Targeting GIRK Channels in Disease.Trends in pharmacological sciences · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nora M McCallGraduate Program in Neuroscience, and.ORCID 0000-0001-5793-1701
Ezequiel Marron Fernandez de VelascoDepartment of Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455.ORCID 0000-0003-0257-4457
Kevin WickmanDepartment of Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455 wickm002@umn.edu.ORCID 0000-0002-5179-9540
University of Minnesota · US

Funding

Relevance and plasticity of inhibitory metabotropic signaling in reward circuitsR01DA034696 · NIDA · UNIVERSITY OF MINNESOTA · PI WICKMAN, KEVIN D · 2013 to 2022
$3.4M
Cocaine-induced adaptations in inhibitory signaling in VTA dopamine neuronsF31DA041767 · NIDA · UNIVERSITY OF MINNESOTA · PI MCCALL, NORA · 2016 to 2018
$116k
NIDA NIH HHS F31 DA041767NIDA NIH HHS R01 DA034696
6 · The paper itself

Abstract

Dopamine (DA) neurons of the VTA have been widely implicated in the cellular and behavioral responses to drugs of abuse. Inhibitory G protein signaling mediated by GABA

Indexed as

AnimalsCocaineDopaminergic NeuronsDopamine Uptake InhibitorsDose-Response Relationship, DrugFemaleG Protein-Coupled Inwardly-Rectifying Potassium ChannelsMaleMiceMice, TransgenicMotor ActivityVentral Tegmental AreaCocaineDopamine Uptake InhibitorsG Protein-Coupled Inwardly-Rectifying Potassium ChannelsD2 dopamine receptordopamineGABABG proteinKir3VTA

Identifiers

PMID30837265
PMCPMC6510348
OpenAlexW2918604195

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.