ArticleBMJ open2019
Association between anxiety, depression and quality of life: study protocol for a systematic review of evidence from longitudinal studies.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Anxiety, depression and acromegaly: a systematic review.Journal of endocrinological investigation · 2025Pooled it
- Anxiety, Depression and Quality of Life-A Systematic Review of Evidence from Longitudinal Observational Studies.International journal of environmental research and public health · 2021Pooled it
- L-Arginine is a feasible supplement to heal chronic anal fissure via reducing internal anal sphincter pressure: a randomized clinical trial study.Amino acids · 2023Trial
- Researchers' Mental Health and Quality of Life: A Protocol for Systematic Review and Meta-Analysis.Health science reports · 2026Article
- Impact of Psychological Factors on Functional Performance among Patients with Chronic Obstructive Pulmonary Disease.International journal of environmental research and public health · 2023Article
- Anxiety and depression and health-related quality of life among adults with migraine: a National Population-Based Study.Frontiers in public health · 2023Article
- Association of 100% Fruit Juice Consumption with Cognitive Measures, Anxiety, and Depression in US Adults.Nutrients · 2022Article
- Article
- Association between Anxiety, Depressive Symptoms, and Quality of Life in Patients Undergoing Diagnostic Flexible Video Bronchoscopy.International journal of environmental research and public health · 2021Observational
- Anxiety and Gastrointestinal Symptoms Related to COVID-19 during Italian Lockdown.Journal of clinical medicine · 2021Article
- The Societal Influences and Quality of Life Among Healthcare Team Members During the COVID-19 Pandemic.Frontiers in psychiatry · 2021Article
- Diet, Exercise, Lifestyle, and Mental Distress among Young and Mature Men and Women: A Repeated Cross-Sectional Study.Nutrients · 2020Article
- Anxiety, Depression and Quality of Life in Older Adults: Trajectories of Influence across Age.International journal of environmental research and public health · 2020Article
- Gastrointestinal health: An investigation of mediating effects on mood and quality of life.Health psychology openArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEvidence from individual longitudinal studies suggests that anxiety and depression may impact quality of life. However, systematic reviews synthesising current evidence have mainly focused on specific samples. Thus, the aim of this study is to synthesise evidence from longitudinal studies on the association between anxiety, depression and quality of life in a systematic review. METHODS AND ANALYSIS: A systematic review of evidence from longitudinal studies analysing the association between anxiety, depression and quality of life will be conducted, taking into account the current Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Several electronic databases from relevant fields of research (PubMed, PsycINFO, PSYNDEX, EconLit, NHS EED) will be searched in September 2018 using defined search terms, with an updated search planned. Moreover, reference lists of included studies will be searched manually. Study eligibility will be appraised in a two-step process against pre-defined inclusion/exclusion criteria. Primarily, information on study design and assessment, statistical methods, participant characteristics as well as results regarding our research question will be extracted. The quality of included studies will be assessed using an appropriate tool. Study selection, data extraction and assessment of study quality will be performed by two reviewers. Disagreements will be resolved through discussion or by inclusion of a third party. Results will be synthesised narratively in text and tables. Depending on the number and heterogeneity of the studies included, a meta-analysis will be performed. ETHICS AND DISSEMINATION: As no primary data will be collected, approval from an ethics committee is not required. Results will be disseminated through conference presentations and publication in a peer-reviewed, scientific journal. PROSPERO REGISTRATION NUMBER: CRD42018108008.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.