Evidence map›Paper›PMID 30837010›Full record

ArticleDevelopment and psychopathology2019

Child maltreatment, adaptive functioning, and polygenic risk: A structural equation mixture model.

Eric L Thibodeau, Katherine E Masyn, Fred A Rogosch, Dante Cicchetti

Abstract read
In one paragraph

Article in Development and psychopathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Eric L ThibodeauUniversity of Minnesota.
Katherine E MasynGeorgia State University.
Fred A RogoschMt. Hope Family Center, University of Rochester.
Dante CicchettiUniversity of Minnesota.

Funding

Chronic Stress of Maltreatment: Drug Use VulnerabilityR01DA017741 · NIDA · UNIVERSITY OF ROCHESTER · PI CICCHETTI, DANTE CICCHETTI, ROGOSCH, FRED A · 2004 to 2016
$5.1M
Child Abuse and Trauma Related Psychopathology: Multiple Levels of AnalysisR01MH083979 · NIMH · UNIVERSITY OF ROCHESTER · PI CICCHETTI, DANTE CICCHETTI, ROGOSCH, FRED A · 2009 to 2013
$3.2M
NIDA NIH HHS R01 DA017741NIMH NIH HHS R01 MH083979
6 · The paper itself

Abstract

This study used a structural equation mixture model to examine associations between child maltreatment, polygenic risk, and indices of adaptive functioning. Children aged 6 to 13 years (N = 1,004), half maltreated, half nonmaltreated, were recruited to attend a research day camp. Multi-informant indicators of prosocial behavior, antisocial behavior, withdrawn behavior, and depression were collected and used in a latent class analysis. Four classes emerged, characterizing "well-adjusted," "externalizing," "internalizing," and "socially dominant" groups. Twelve genetic variants, previously reported in the Gene × Environment literature, were modeled as one weighted polygenic risk score. Large main effects between maltreatment and adaptive functioning were observed (Wald = 35.3, df = 3, p < .0001), along with evidence of a small Gene × Environment effect (Wald = 13.5, df = 3, p = .004), adjusting for sex, age, and covariate interaction effects.

Indexed as

Defense MechanismsSocial AdjustmentAdolescentChildChild AbuseDepressionFemaleHumansMaleMultifactorial InheritanceProblem Behavior

Identifiers

PMID30837010
PMCPMC6988177

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.