Evidence map›Paper›PMID 30836701›Full record

ArticleJournal of functional biomaterials2019

Fabrication of Porous Bone Scaffolds Using Alginate and Bioactive Glass.

Jonathan Hatton, Graham Roy Davis, Abdel-Hamid I Mourad, Nizamudeen Cherupurakal, Robert G Hill, Sahar Mohsin

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  17. Biomimetic Aspects of Oral and Dentofacial Regeneration.Biomimetics (Basel, Switzerland) · 2020
    Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jonathan HattonDental Physical Sciences Unit, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 4NS, UK. jonathanrhatton@gmail.com.
Graham Roy DavisDental Physical Sciences Unit, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 4NS, UK. g.r.davis@qmul.ac.uk.
Abdel-Hamid I MouradDepartment of Mechanical Engineering, College of Engineering, UAEU Al Ain, 15551, UAE. ahmourad@uaeu.ac.ae.
Nizamudeen CherupurakalDepartment of Mechanical Engineering, College of Engineering, UAEU Al Ain, 15551, UAE. nizam.ac@uaeu.ac.ae.
Robert G HillDental Physical Sciences Unit, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 4NS, UK. r.hill@qmul.ac.uk.
Sahar MohsinDental Physical Sciences Unit, Institute of Dentistry, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, E1 4NS, UK. smohsin@uaeu.ac.ae.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porous composite scaffold using an alginate and bioactive glass ICIE16M was synthesized by a simple freeze-drying technique. The scaffold was characterized using compression testing, Fourier-transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), X-ray diffraction (XRD), X-ray microtomography (XMT) and scanning electron microscopy (SEM). The bioactivity of the scaffold was evaluated by its ability to form apatite on its surface in simulated body fluid (SBF). The data collected showed evidence that the novel material produced had an appropriate pore size for osteoconduction, with an average pore size of 110 µm and maximum pore size of 309 µm. Statistical analysis confirmed that the glass filler significantly (P < 0.05) increased the collapse yield of the scaffolds compared with pure alginate scaffolds. The ICIE16M glass had an amorphous structure, favorable for bioactivity.

Indexed as

alginatebioactive glassbone scaffoldsfreeze-dryingporousstrontium

Identifiers

PMID30836701
PMCPMC6462929

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.