Evidence map›Paper›PMID 30836664›Full record

ArticleNutrients2019

Improvement in Diabetic Retinopathy through Protection against Retinal Apoptosis in Spontaneously Diabetic Torii Rats Mediated by Ethanol Extract of

Chan-Sik Kim, Junghyun Kim, Young Sook Kim, Kyuhyung Jo, Yun Mi Lee, Dong Ho Jung, Ik Soo Lee, Joo-Hwan Kim, Jin Sook Kim

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Molecules (Basel, Switzerland) · 2020
    Article
  7. Article
  8. Therapeutic Effect ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Chan-Sik KimClinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. chskim@kiom.re.kr.ORCID 0000-0001-7610-9887
Junghyun KimHerbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. dvmhyun@jbnu.ac.kr.ORCID 0000-0002-9003-2158
Young Sook KimKorean Convergence Medicine, University of Science and Technology (UST), Daejeon 34113, Korea. ykim@kiom.re.kr.
Kyuhyung JoClinical Medicine Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. jopd7414@kiom.re.kr.
Yun Mi LeeHerbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. candykomg@kiom.re.kr.
Dong Ho JungHerbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. jdh9636@kiom.re.kr.
Ik Soo LeeHerbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. knifer48@kiom.re.kr.
Joo-Hwan KimDepartment of Life Science. Gachon University, 1342, Seongnamdaero, Seongnam, Gyeonggido 13120, Korea. kimjh2009@gachon.ac.kr.
Jin Sook KimHerbal Medicine Research Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea. jskim@kiom.re.kr.
Gachon University · KRKorea Institute of Oriental Medicine · KR

Funding

Korea Institute of Oriental Medicine K17270 & K18270
6 · The paper itself

Abstract

Retinal apoptosis plays a critical role in the progression of diabetic retinopathy (DR), a common diabetic complication. Currently, the tight control of blood glucose levels is the standard approach to prevent or delay the progression of DR. However, prevalence of DR among diabetic patients remains high. Focusing on natural nutrients or herbal medicines that can prevent or delay the onset of diabetic complications, we administered an ethanol extract of the aerial portion of

Indexed as

AnimalsApoptosisDiabetes MellitusDiabetic RetinopathyDrugs, Chinese HerbalEndothelial CellsEthanolGlycation End Products, AdvancedHumansMalePlant ExtractsRatsRetinaDrugs, Chinese HerbalEthanolGlycation End Products, AdvancedPlant Extractsadjunctive effectadvanced glycation end products (AGEs)combination therapydiabetic retinopathy (DR)human retinal microvascular endothelial cells (HRMECs)mitochondrial functionOsteomeles schwerinaeoxidative stressretinal apoptosisspontaneously diabetic Torii (SDT) rat

Identifiers

PMID30836664
PMCPMC6470872
OpenAlexW2913747551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.