Evidence map›Paper›PMID 30836628›Full record

ArticleNutrients2019

Association between Neonatal Whole Blood Iron Content and Cytokines, Adipokines, and Other Immune Response Proteins.

Steffen U Thorsen, Christian B Pipper, Christina Ellervik, Flemming Pociot, Julie N Kyvsgaard, Jannet Svensson

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Steffen U ThorsenCopenhagen Diabetes Research Center (CPH-DIRECT), Department of Paediatrics, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730 Herlev, Denmark. s.u.thorsen@gmail.com.ORCID 0000-0003-4783-2931
Christian B PipperDepartment of Public Health, Section of Biostatistics, University of Copenhagen, Copenhagen, Oester Farimagsgade 5, 1710 Copenhagen K, Denmark. pipper@sund.ku.dk.ORCID 0000-0003-0261-616X
Christina EllervikDepartment of Production, Research, and Innovation, Region Zealand, Alleen 15, 4180 Sorø, Denmark. christina@ellervik.dk.ORCID 0000-0002-3088-4375
Flemming PociotCopenhagen Diabetes Research Center (CPH-DIRECT), Department of Paediatrics, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730 Herlev, Denmark. flemming.pociot.01@regionh.dk.ORCID 0000-0003-3274-5448
Julie N KyvsgaardCopenhagen Diabetes Research Center (CPH-DIRECT), Department of Paediatrics, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730 Herlev, Denmark. juliekyvs@hotmail.com.
Jannet SvenssonCopenhagen Diabetes Research Center (CPH-DIRECT), Department of Paediatrics, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730 Herlev, Denmark. Jannet.Svensson@regionh.dk.ORCID 0000-0002-9365-0728
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: High iron associates with inflammation and type 1 diabetes (T1D). Iron is essential not only for neonatal development but also for infectious microorganisms. The neonatal immune system is immature, and innate immunity prevails before immunocompetence develops. (2) Methods: In 398 newborns from the Danish Newborn Screening Biobank, we examined if whole blood iron (WB-Iron) content were associated with cytokines, adipokines, C-reactive protein (CRP), and mannose-binding lectin (MBL) in non-infected healthy neonates, and if these associations differed in newborns who later developed T1D (cases) (

Indexed as

AdipokinesBiological Specimen BanksBiomarkersC-Reactive ProteinCytokinesDenmarkDiabetes Mellitus, Type 1FemaleHealthy VolunteersHumansImmunity, InnateInfant, NewbornInfant, Newborn, DiseasesInterleukin-6IronMaleAdipokinesBiomarkersC-Reactive ProteinCytokinesInterleukin-6IronMannose-Binding LectinadipokinesC-reactive proteincytokinesdiabetes mellitushumaninfantironmannose-binding lectinnewbornTREM1type 1

Identifiers

PMID30836628
PMCPMC6470999
OpenAlexW2919233476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.