ArticlePloS one2019
The validity, reliability and minimal clinically important difference of the patient specific functional scale in snake envenomation.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Outcomes in intervention research on snakebite envenomation: a systematic review.F1000Research · 2022Pooled it
- Clinical outcomes and outcome measurement tools reported in randomised controlled trials of treatment for snakebite envenoming: A systematic review.PLoS neglected tropical diseases · 2021Pooled it
- Oral varespladib for the treatment of snakebite envenoming in India and the USA (BRAVO): a phase II randomised clinical trial.BMJ global health · 2024Trial
- Long-Term Clinical Outcomes of Rattlesnake Envenomation in Arizona Following Treatment With Crofab vs Anavip: A Retrospective Observational Study.Journal of the American College of Emergency Physicians open · 2025Article
- Evaluation of the Patient-Specific Functional Scale for monitoring paediatric injury patients at a zonal referral hospital in Northern Tanzania.BMJ paediatrics open · 2025Article
- Cross cultural adaptation and validation of the Hindi version of foot function index.Chiropractic & manual therapies · 2024Article
- Functional Disability at 3 Months in Patients with Residual Limb Swelling after Snakebite Envenoming.The American journal of tropical medicine and hygiene · 2024Article
- Article
- A simple mortality risk prediction score for viper envenoming in India (VENOMS): A model development and validation study.PLoS neglected tropical diseases · 2022Article
- Contextualizing the Impact of Snakebite Envenoming on Patients: A Qualitative Content Analysis of Patient-Specific Functional Scale Activities Using the International Classification of Functioning, Disability and Health.International journal of environmental research and public health · 2021Article
- Chronic health effects and cost of snakebite.Toxicon: X · 2021Article
- Validity and reliability of telephone administration of the patient-specific functional scale for the assessment of recovery from snakebite envenomation.PLoS neglected tropical diseases · 2019Article
- Current Management of Copperhead Snakebites in Missouri.Missouri medicineArticle
Corrections and comments
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Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveValid, reliable, and clinically relevant outcome measures are necessary in clinical studies of snake envenomation. The aim of this study was to evaluate the psychometric (validity and reliability) and clinimetric (minimal clinically important difference [MCID]) properties of the Patient-Specific Functional Scale (PSFS) in snakebite envenomation.
methodsWe performed a secondary analysis of two existing snakebite trials that measured clinical outcomes using the PSFS as well as other quality of life and functional assessments. Data were collected at 3, 7, 10, and 17 days. Reliability was determined using Cronbach's alpha for internal consistency and the intraclass correlation coefficient (ICC) for temporal stability at 10 and 17 days. Validity was assessed using concurrent validity correlating with the other assessments. The MCID was evaluated using the following criteria: (1) the distribution of stable patients according to both standard error of measurement (SEM) and responsiveness techniques, and (2) anchor-based methods to compare between individuals and to detect discriminant ability of a positive change with a receiver operator characteristic (ROC) curve and optimal cutoff point.
resultsA total of 86 patients were evaluated in this study. The average PSFS scores were 5.37 (SD 3.23), 7.95 (SD 2.22), and 9.12 (SD 1.37) at 3, 7, and 10 days, respectively. Negligible floor effect was observed (maximum of 8% at 3 days); however, a ceiling effect was observed at 17 days (25%). The PSFS showed good reliability with an internal consistency of 0.91 (Cronbach's alpha) (95% CI 0.88, 0.95) and a temporal stability of 0.83 (ICC) (95% CI 0.72, 0.89). The PSFS showed a strong positive correlation with quality of life and functional assessments. The MCID was approximately 1.0 for all methods.
conclusionsWith an MCID of approximately 1 point, the PSFS is a valid and reliable tool to assess quality of life and functionality in patients with snake envenomation.
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