ArticlePLoS biology2019
A polyploid admixed origin of beer yeasts derived from European and Asian wine populations.
Article in PLoS biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 83 citations in OpenAlex.
- CYClones: a highly powered, fully genotyped, eight-parent yeast mapping population.G3 (Bethesda, Md.) · 2026Article
- Genomic Evidence of Early-Diverging Domesticated Lineages in Norwegian Farmhouse Yeast.Genome biology and evolution · 2026Article
- Genotypic and Phenotypic Diversity of Maudiozyma humilis: The Multiple Evolutionary Trajectories of a Domesticated Yeast.Genome biology and evolution · 2026Article
- From Oak to Wine: Evolution, Admixture, and Adaptation of California and British Columbia Saccharomyces Cerevisiae Wine Strains.Genome biology and evolution · 2026Article
- Distinctive domestication of farmhouse beer yeasts preserved pre-industrial genetic and phenotypic diversity.Current biology : CB · 2026Article
- Mutations and Metabolic Factors Affecting Interaction of Toxigenic and AtoxigenicMicroorganisms · 2026Article
- Phylogenomic diversity of clinicalMicrobiology spectrum · 2026Article
- Genomic tales of wine yeasts: from domestication to functional innovation.FEMS yeast research · 2026Review
- Life beyond 6000 genes: from sequence to synthesis in a post-genomics era.FEMS yeast research · 2026Review
- Distribution of yeast species and their resistance to copper and sulfite across arboreal and viticulture habitats.FEMS yeast research · 2026Article
- From one genome to thousands, and beyond.FEMS yeast research · 2026Review
- CYClones: A highly powered, fully genotyped, 8-parent yeast mapping population.bioRxiv : the preprint server for biology · 2025Article
- Footprints of Human Migration in the Population Structure of Wild Baker's Yeast.Molecular ecology · 2025Article
- Colonization of vineyards by non-bioRxiv : the preprint server for biology · 2025Article
- Horizontal Transfer and Recombination Fuel Ty4 Retrotransposon Evolution in Saccharomyces.Genome biology and evolution · 2025Article
- Effects of regional location on the genotype and phenotype of historical Irish brewing yeast.Frontiers in microbiology · 2025Article
- Overview of the Saccharomyces cerevisiae population structure through the lens of 3,034 genomes.G3 (Bethesda, Md.) · 2024Article
- European farmhouse brewing yeasts form a distinct genetic group.Applied microbiology and biotechnology · 2024Article
- Recombination, admixture and genome instability shape the genomic landscape of Saccharomyces cerevisiae derived from spontaneous grape ferments.PLoS genetics · 2024Article
- The origins of the Guinness stout yeast.Communications biology · 2024Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Strains of Saccharomyces cerevisiae used to make beer, bread, and wine are genetically and phenotypically distinct from wild populations associated with trees. The origins of these domesticated populations are not always clear; human-associated migration and admixture with wild populations have had a strong impact on S. cerevisiae population structure. We examined the population genetic history of beer strains and found that ale strains and the S. cerevisiae portion of allotetraploid lager strains were derived from admixture between populations closely related to European grape wine strains and Asian rice wine strains. Similar to both lager and baking strains, ale strains are polyploid, providing them with a passive means of remaining isolated from other populations and providing us with a living relic of their ancestral hybridization. To reconstruct their polyploid origin, we phased the genomes of two ale strains and found ale haplotypes to both be recombinants between European and Asian alleles and to also contain novel alleles derived from extinct or as yet uncharacterized populations. We conclude that modern beer strains are the product of a historical melting pot of fermentation technology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.