Evidence map›Paper›PMID 30835490›Full record

ArticleAssay and drug development technologies2019

Electrophysiological and Pharmacological Characterization of Human Inwardly Rectifying K

Camille Sanson, Brigitte Schombert, Bruno Filoche-Rommé, Michel Partiseti, G Andrees Bohme

Open access · hybridAbstract read
In one paragraph

Article in Assay and drug development technologies, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. The network of cardiac KNaunyn-Schmiedeberg's archives of pharmacology · 2024
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Methadone Blockade of Cardiac Inward Rectifier KJournal of the American Heart Association · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Cardioprotection of an IAmerican journal of translational research · 2021
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Camille Sanson1 Integrated Drug Discovery, High-Content Biology, Sanofi Research and Development, Vitry-sur-Seine, France.
Brigitte Schombert1 Integrated Drug Discovery, High-Content Biology, Sanofi Research and Development, Vitry-sur-Seine, France.
Bruno Filoche-Rommé2 Integrated Drug Discovery, Medicinal Chemistry, Sanofi Research and Development, Vitry-sur-Seine, France.
Michel Partiseti1 Integrated Drug Discovery, High-Content Biology, Sanofi Research and Development, Vitry-sur-Seine, France.
G Andrees Bohme1 Integrated Drug Discovery, High-Content Biology, Sanofi Research and Development, Vitry-sur-Seine, France.
Sanofi (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inwardly rectifying I

Indexed as

AutomationAnimalsChloroquineCHO CellsCricetulusDose-Response Relationship, DrugElectrophysiological PhenomenaHumansImidazolesMolecular StructurePentamidinePhenanthrolinesPotassium Channels, Inwardly Rectifying2-(2-methyl-1H-indol-3-yl)-1H-imidazol(4,5-f)(1,10)phenanthrolineChloroquineImidazolesKCNJ2 protein, humanPentamidinePhenanthrolinesPotassium Channels, Inwardly RectifyingCiPA initiativeK channelssafety pharmacologysudden deathtorsades de pointesventricular arrhythmia

Identifiers

PMID30835490
PMCPMC6479253
OpenAlexW2918655591

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.