ReviewRadiology2019
Hyperpolarized
Registry-linked trialOpen access · greenAbstract readReview
In one paragraph
Review in Radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05697406 (Hyperpolarized 13-C Pyruvate MRI Surveillance of Multiple Cancers), which is not on this map. Cited by 190 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
190citing papers in PubMed, 2 pooled it
17.9field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
NCT05697406 phase1 / phase2recruitingnot on this mapstarted 2024, after this paper: background citation
Hyperpolarized 13-C Pyruvate MRI Surveillance of Multiple Cancers
Who cites it
190 citing papers in PubMed, 2 syntheses or guidelines pooled it, 327 citations in OpenAlex.
- Metabolic Imaging as Future Technology and Innovation in Brain-Tumour Surgery: A Systematic Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- Advances and prospects in deuterium metabolic imaging (DMI): a systematic review of in vivo studies.European radiology experimental · 2024Pooled it
- Enhanced Glioblastoma Detection ThroughMagnetic resonance in medicine · 2026Article
- Multi-Vendor and Multi-Site Characterization ofMagnetic resonance in medicine · 2026Article
- From equilibrium to dynamic metabolic imaging: the evolving role of magnetic resonance spectroscopic imaging in neurodegenerative disorders.Journal of translational medicine · 2026Review
- Stable isotopes from Earth science to bedside medicine: beyond tracers and toward mechanistic biomarkers in medical oncology.Medical oncology (Northwood, London, England) · 2026Review
- A Static Phantom for Harmonization of Hyperpolarized [1-Magnetic resonance in medicine · 2026Article
- Molecular Imaging of In Vivo Zinc Distribution Using Nuclear and Magnetic Resonance Imaging.Chemical & biomedical imaging · 2026Review
- Differential activation of TCA cycle activity and PDH flux by dichloroacetate in skeletal muscle measured by hyperpolarized [2-iScience · 2026Article
- Minute-Scale Repeated Metabolic Probing of Living Cells Enabled by Rapid Parahydrogen-Based Hyperpolarization.Angewandte Chemie (International ed. in English) · 2026Article
- Hyperpolarized γ-Glutamyl-[1-Molecular imaging and biology · 2026Article
- Clinical Applications of Hyperpolarized Magnetic Resonance Imaging in Brain Tumors: Current Evidence and Future Opportunities.Cancers · 2026Review
- First worldwide multicenter validation of the POLARIS preclinical polarizer across biological models and imaging paradigms.Research square · 2026Article
- Illuminating aging with multimodal optical metabolic imaging.Science advances · 2026Review
- Optimized Detection of Left Ventricular Hyperpolarized [1-Magnetic resonance in medicine · 2026Article
- In vivo dynamic nuclear polarization magnetic resonance imaging reveals cardiac mitochondrial redox imbalance as an early indicator of heart failure.Redox biology · 2026Article
- [Glycolytic Reprogramming in Lung Adenocarcinoma: Molecular Mechanisms, Metabolic Biomarkers and Targeted Therapeutic Strategies].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2026Review
- Increasing Infusion Times of Hyperpolarized [1-Magnetic resonance in medicine · 2026Article
- Ultra-low fieldCommunications chemistry · 2026Article
- Pharmacokinetic modeling strategies for dynamic hyperpolarized urea imaging.Magnetic resonance in medicine · 2026Article
130 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Zhen J WangFrom the Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143.ORCID 0000-0002-2065-5296
Michael A OhligerFrom the Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143.
Peder E Z LarsonFrom the Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143.
Jeremy W GordonFrom the Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143.
Robert A BokFrom the Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143.ORCID 0000-0003-1737-9056
James SlaterFrom the Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143.
Javier E Villanueva-MeyerFrom the Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143.
Christopher P HessFrom the Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143.ORCID 0000-0002-5132-5302
John KurhanewiczFrom the Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143.
Daniel B VigneronFrom the Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94143.ORCID 0000-0001-5795-8699
University of California, San Francisco · US
Funding
Project 4: Multi-modality Metabolic Imaging for Monitoring Molecular Sub-types of GliomaP01CA118816 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Susan M Chang, Janine Marie Lupo · 2007 to 2026
$44.7MTR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Daniel B Vigneron · 2011 to 2026
$19.9MDevelopment and Translation of Hyperpolarized C-13 Prostate Cancer MRI MethodsR01EB017449 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KURHANEWICZ, JOHN, VIGNERON, DANIEL B · 2013 to 2017
$5.9MTranslating HP 13C MRI as a Novel Paradigm for Assessing Drug Target InhibitionR01CA183071 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HURD, RALPH EUGENE, MUNSTER, PAMELA N. · 2014 to 2018
$3.3MNovel hyperpolarized 13C molecular imaging techniques for differentiating NAFLD and NASHR01DK115987 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI OHLIGER, MICHAEL, VON MORZE, CORNELIUS · 2018 to 2022
$2.1MHyperpolarized C-13 Diffusion MRI Measures of Cellular Transport and MetabolismR01EB016741 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LARSON, PEDER ERIC ZUFALL · 2014 to 2017
$2.0MHyperpolarized 13C Markers of Diabetic Nephropathy and Treatment ResponseR01DK097357 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WANG, ZHEN JANE · 2013 to 2017
$1.2MNCI NIH HHS P01 CA118816NCI NIH HHS R01 CA183071NIBIB NIH HHS P41 EB013598NIBIB NIH HHS R01 EB016741NIBIB NIH HHS R01 EB017449NIDDK NIH HHS R01 DK097357NIDDK NIH HHS R01 DK115987
Abstract
Hyperpolarized (HP) carbon 13 (
Indexed as
Carbon IsotopesImage Interpretation, Computer-AssistedMagnetic Resonance ImagingCardiovascular DiseasesHumansMetabolic DiseasesModels, BiologicalNeoplasmsCarbon-13Carbon Isotopes
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT05697406ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.