Evidence map›Paper›PMID 30835066›Full record

ArticleEnvironmental science and pollution research international2020

Effects of glyphosate and a commercial formulation Roundup® exposures on maturation of Xenopus laevis oocytes.

Sylvain Slaby, Pauline Titran, Guillaume Marchand, Julie Hanotel, Arlette Lescuyer, Alain Leprêtre, Jean-François Bodart, Matthieu Marin, Sébastien Lemiere

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Highly Diluted Glyphosate Mitigates Its Effects onInternational journal of molecular sciences · 2023
    Article
  2. Roundup in the Reproduction of Crucian Carp (Animals : an open access journal from MDPI · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sylvain SlabyCNRS, INRA, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, University Lille, F-59000, Lille, France.
Pauline TitranCNRS, INRA, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, University Lille, F-59000, Lille, France.
Guillaume MarchandCNRS, INRA, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, University Lille, F-59000, Lille, France.
Julie HanotelCNRS, INRA, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, University Lille, F-59000, Lille, France.
Arlette LescuyerCNRS, INRA, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, University Lille, F-59000, Lille, France.
Alain LeprêtreEA 4515-LGCgE-Laboratoire Génie Civil et géo-Environnement, Cité scientifique, SN3, University Lille, F-59655, Villeneuve d'Ascq, France.
Jean-François BodartCNRS, INRA, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, University Lille, F-59000, Lille, France.
Matthieu MarinCNRS, INRA, UMR 8576-UGSF-Unité de Glycobiologie Structurale et Fonctionnelle, University Lille, F-59000, Lille, France.
Sébastien LemiereEA 4515-LGCgE-Laboratoire Génie Civil et géo-Environnement, Cité scientifique, SN3, University Lille, F-59655, Villeneuve d'Ascq, France. sebastien.lemiere@univ-lille.fr.ORCID http://orcid.org/0000-0002-6782-5344
Centre National de la Recherche Scientifique · FRLaboratoire de Mécanique et Génie Civil · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pesticides are often found at high concentrations in small ponds near agricultural field where amphibians are used to live and reproduce. Even if there are many studies on the impacts of phytopharmaceutical active ingredients in amphibian toxicology, only a few are interested in the earlier steps of their life cycle. While their populations are highly threatened with extinction. The aim of this work is to characterize the effects of glyphosate and its commercial formulation Roundup® GT Max on the Xenopus laevis oocyte maturation which is an essential preparation for the laying and the fertilization. Glyphosate is an extensively used herbicide, not only known for its effectiveness but also for its indirect impacts on non-target organisms. Our results showed that exposures to both forms of glyphosate delayed this hormone-dependent process and were responsible for spontaneous maturation. Severe and particular morphogenesis abnormalities of the meiotic spindle were also observed. The MAPK pathway and the MPF did not seem to be affected by exposures. The xenopus oocyte is particularly affected by the exposures and appears as a relevant model for assessing the effects of environmental contamination.

Indexed as

AnimalsGlycineGlyphosateHerbicidesOocytesXenopus laevisGlycineGlyphosateHerbicidesAmphibian toxicologyGlyphosateMaturationOocytePesticideRoundupXenopus

Identifiers

PMID30835066
OpenAlexW2919098286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.