ArticleJournal of biomedical optics2019
Optimized depth-resolved estimation to measure optical attenuation coefficients from optical coherence tomography and its application in cerebral damage determination.
Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Structural and Angiographic Assessment of the Nerve Fiber Layer in Age-Related Macular Degeneration and Diabetic Retinopathy.Investigative ophthalmology & visual science · 2026Article
- Identification and quantification of oral lymphatic vessel networks using optical coherence tomography (OCT).Biomedical optics express · 2026Article
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- Segmental airway adenocarcinoma-simulating phantom for endoscopic near-infrared optical coherence tomography.Journal of biomedical optics · 2025Article
- Leveraging pretrained vision transformers for automated cancer diagnosis in optical coherence tomography images.Biomedical optics express · 2025Article
- Quantitative assessment of retinal attenuation and backscattering in OCT imaging using iterative layer-based analysis.Biomedical optics express · 2025Article
- Dual-parameter tomographic imaging of attenuation and backscattering coefficients for quantitative evaluation of immune cell-mediated cytotoxicity in tumor spheroids.Theranostics · 2025Article
- Optical attenuation coefficient decorrelation-based optical coherence tomography angiography for microvascular evaluation of Alzheimer's disease on mice.Neurophotonics · 2025Article
- Accurate attenuation characterization in optical coherence tomography using multi-reference phantoms and deep learning.Biomedical optics express · 2024Article
- Multimodal Optical Imaging of Ex Vivo Fallopian Tubes to Distinguish Early and Occult Tubo-Ovarian Cancers.Cancers · 2024Article
- Imaging Biomarkers of Oral Dysplasia and Carcinoma Measured with In Vivo Endoscopic Optical Coherence Tomography.Cancers · 2024Article
- Unleashing the power of optical attenuation coefficients to facilitate segmentation strategies in OCT imaging of age-related macular degeneration: perspective.Biomedical optics express · 2023Article
- Depth-dependent attenuation and backscattering characterization of optical coherence tomography by stationary iterative method.Journal of biomedical optics · 2023Article
- Accuracy and precision of depth-resolved estimation of attenuation coefficients in optical coherence tomography.Journal of biomedical optics · 2023Article
- Article
- Using beam-offset optical coherence tomography to reconstruct backscattered photon profiles in scattering media.Biomedical optics express · 2022Article
- Depth-resolved extraction of optical attenuation for glaucoma assessment in clinical settings: a pilot study.Biomedical optics express · 2022Article
- Optical Coherence Tomography Measurements of the Retinal Pigment Epithelium to Bruch Membrane Thickness Around Geographic Atrophy Correlate With Growth.American journal of ophthalmology · 2022Observational
- Automatic geographic atrophy segmentation using optical attenuation in OCT scans with deep learning.Biomedical optics express · 2022Article
- Differentiation of otitis media-causing bacteria and biofilmsFrontiers in cellular and infection microbiology · 2022Article
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9 authors.
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Abstract
The optical attenuation coefficient (OAC) reflects the optical properties of various tissues or tissues of the same type under different physiological conditions. Quantitative measurement of OAC from optical coherence tomography (OCT) signals can provide additional information and can increase the potential for OCT applications. We present an optimized depth-resolved estimation (ODRE) method that derives a precise mapping between the measured OCT signal and the OAC. In contrast to previous depth-resolved estimation (DRE) methods, the optimized method can estimate the OAC in any depth range and ignore whether the light is completely attenuated. Numerical simulations and phantom experiments are used to verify its validity, and this method is applied to detect cerebral damage. In combination with OCT angiography, real-time observation of the change of blood perfusion and the degree of cerebral damage in mice with focal cerebral ischemia provides important information to help us understand the temporal relationship between brain damage and ischemia.
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