ArticleJournal of oral biology and craniofacial research
Effect of periodontal therapy on disease activity in patients of rheumatoid arthritis with chronic periodontitis.
Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- The Effects of Periodontal Treatment on Rheumatoid Arthritis and of Anti-Rheumatic Drugs on Periodontitis: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Non-surgical periodontal treatment improves rheumatoid arthritis disease activity: a meta-analysis.Clinical oral investigations · 2021Pooled it
- Association Between Rheumatoid Arthritis Disease Activity and Periodontitis Defined by Tooth Loss: Longitudinal and Cross-Sectional Data From Two Observational Studies.Arthritis care & research · 2025Observational
- Oral Microbiome Dysbiosis and Citrullination in Rheumatoid Arthritis.Advances in experimental medicine and biology · 2025Review
- Molecular Mimicry Between Gut Microbiome and Rheumatoid Arthritis: Current Concepts.Medical sciences (Basel, Switzerland) · 2024Review
- Periodontitis and periodontopathic bacteria as risk factors for rheumatoid arthritis: A review of the last 10 years.The Japanese dental science review · 2023Review
- Associations between inflammation-related LL-37 with subgingival microbial dysbiosis in rheumatoid arthritis patients.Clinical oral investigations · 2022Article
- Review
- The Effects of Non-Surgical Periodontitis Therapy on the Clinical Features and Serological Parameters of Patients Suffering from Rheumatoid Arthritis as Well as Chronic Periodontitis.Journal of inflammation research · 2022Article
- Does periodontal treatment improve rheumatoid arthritis disease activity? A systematic review.Rheumatology advances in practice · 2022Review
- Does non-surgical periodontal treatment influence on rheumatoid arthritis? A systematic review and meta-analysis.The Saudi dental journal · 2021Review
- Should We Be Screening for and Treating Periodontal Disease in Individuals Who Are at Risk of Rheumatoid Arthritis?Healthcare (Basel, Switzerland) · 2021Review
- Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase.International journal of oral science · 2021Article
- Does periodontitis affect the treatment response of biologics in the treatment of rheumatoid arthritis?Arthritis research & therapy · 2020Article
- Periodontitis and cardiovascular diseases: Consensus report.Journal of clinical periodontology · 2020Review
- Impact of non-surgical periodontal therapy on serum Resistin and periodontal pathogen in periodontitis patients with obesity.BMC oral health · 2020Article
- Periodontitis and Cardiovascular Diseases. Consensus Report.Global heart · 2020Review
- Non-surgical oral hygiene interventions on disease activity of Rheumatoid arthritis patients with periodontitis: A randomized controlled trial.Journal of dental research, dental clinics, dental prospects · 2020Article
- Linkage of Periodontitis and Rheumatoid Arthritis: Current Evidence and Potential Biological Interactions.International journal of molecular sciences · 2019Review
- Effects of nonsurgical periodontal therapy in patients with rheumatoid arthritis: a prospective before and after study.Colombia medica (Cali, Colombia)Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEvidence have been proposed a positive association between severity of Periodontitis and Rheumatoid arthritis (RA) activity, individuals with advanced RA are more likely to develop periodontal problems compared to their non-RA counterparts, and vice versa. Studies have been suggested that RA manifest as a result of an inflammatory imbalance and autoimmunity. In this perspective, treatment modalities that lead to inhibition of proinflammatory mediators, may prove beneficial for reducing the severity of RA. This study examined the effects of non surgical periodontal therapy (NSPT) on disease activity of RA.
methodsDiagnosed patients of active rheumatoid arthritis with chronic periodontitis were recruited in this study and divided in to treatment and controls groups, both groups were similar in all demographics assessed. Treatment group (n = 20) and controls group (n = 20) underwent assessment for periodontal clinical parameters (plaque index, gingival index, probing pocket depth, clinical attachment level), Rheumatologic clinical (simplified disease activity index) and biochemical parameters(C-reactive protein, Rheumatoid factor, Anti-cyclic citrullinated protein) at baseline and 8 weeks. Serum levels of biochemical parameters were measured by enzyme-linked immunosorbent assay (ELISA).
resultsThe statistically significant (p < 0.001) reduction observed in mean values of PI, GI, PPD, CAL, SDAI in treatment group at 8weeks after NSPT as compare to control group. However serum level of ACCPA, CRP and RF did not show statistically significant (p > 0.05) changes from baseline to reassessment (8 weeks) in both groups.
conclusionsThe improvement in RA disease activity may occurs after non surgical periodontal therapy.
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