Evidence map›Paper›PMID 30834179›Full record

ArticlePeerJ2019

Chemical composition, antioxidant and hepatoprotective activities of methanol extracts from leaves of

Mansour Sobeh, Mona F Mahmoud, Rehab A Hasan, Mohamed A O Abdelfattah, Samir Osman, Harun-Or Rashid, Assem M El-Shazly, Michael Wink

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
7.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
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  8. Caper (Frontiers in pharmacology · 2022
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  11. Biomolecules · 2020
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  12. Piquiá Shells (Oxidative medicine and cellular longevity · 2020
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  14. Suppressive Effects of Octyl Gallate onMolecules (Basel, Switzerland) · 2019
    Article
  15. A Comprehensive Review of the Structure Elucidation of Tannins fromEvidence-based complementary and alternative medicine : eCAM · 2019
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

Mansour SobehInstitute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany.ORCID 0000-0002-2719-8534
Mona F MahmoudDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Rehab A HasanDepartment of Histology, Faculty of Medicine for Girls, Al Azhar University, Cairo, Egypt.
Mohamed A O AbdelfattahDepartment of Science, College of Engineering and Technology, American University of the Middle East, Kuwait.
Samir OsmanDepartment of Pharmacognosy, Faculty of Pharmacy, October 6 University, Cairo, Egypt.
Harun-Or RashidBiotechnology Division, Bangladesh Institute of Nuclear Agriculture Bangladesh, Mymensingh, Bangladesh.
Assem M El-ShazlyDepartment of Pharmacognosy, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt.
Michael WinkInstitute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany.ORCID 0000-0002-7875-4510
Heidelberg University · DEZagazig University · EGAl-Azhar University · EGAmerican University of the Middle East · KWBangladesh Agricultural University · BDOctober 6 University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPlants belonging to the genus

methodsThe secondary metabolites of

resultsA total of 85 secondary metabolites were identified in the leaf extracts of both species. Ellagitannins such as corilagin, chebulagic acid, galloylpunicalagin, and digalloyl-hexahydroxydiphenoyl-hexoside were found to be the major components in DISCUSSION: The antioxidant and hepatoprotective activities exhibited by the studied extracts might be attributed to the high content of the polyphenols. The anti-apoptotic activity could be due to the interference with the apoptotic pathway mediated by Bcl-2: Bim interaction. These findings support the medicinal relevance of

Indexed as

Anti-apoptoticHepatoprotectionHPLC-MS/MSPolyphenolsTerminalia belliricaTerminalia sericea

Identifiers

PMID30834179
PMCPMC6397638
OpenAlexW2916856689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.