Evidence map›Paper›PMID 30834110›Full record

ArticleClinical and translational allergy2019

Characterization of a subgroup of non-type 2 asthma with cow's milk hypersensitivity in young subjects.

N Tsolakis, L Nordvall, C Janson, N Rydell, A Malinovschi, K Alving

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational allergy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

N Tsolakis1Department of Women's and Children's Health, Uppsala University Hospital, Uppsala University, 751 85 Uppsala, Sweden.
L Nordvall1Department of Women's and Children's Health, Uppsala University Hospital, Uppsala University, 751 85 Uppsala, Sweden.
C Janson2Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.
N Rydell3Thermo Fisher Scientific, ImmunoDiagnostics, Uppsala, Sweden.
A Malinovschi2Department of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.
K Alving1Department of Women's and Children's Health, Uppsala University Hospital, Uppsala University, 751 85 Uppsala, Sweden.
Uppsala University Hospital · SEThermo Fisher Scientific (Sweden) · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAsthma with atopy is often characterized by type 2 inflammation but less progress has been made in defining non-type 2 asthma. We have previously identified a subgroup of young non-atopic asthmatics with perceived food hypersensitivity and poor asthma control.

objectiveOur aim was to further characterize this subgroup of non-type 2 asthmatics, including the use of a broad panel of inflammation-related proteins.

methodsSex- and age-matched subjects (10-35 years old) were divided into three groups with regard to history of asthma and atopy: non-atopic asthmatics with perceived cow's milk hypersensitivity but with IgE antibodies < 0.35 kU

resultsNAA had lower FeNO (

conclusionIn a subgroup of non-atopic young asthmatics with perceived cow's milk hypersensitivity we observed poor asthma-related quality of life, airway hyperresponsiveness, and clinically relevant non-type 2 inflammation. MMP-1 was elevated in this group, which deserves further studies.

Identifiers

PMID30834110
PMCPMC6385459
OpenAlexW2918072586

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.