Evidence map›Paper›PMID 30834101›Full record

ArticleJournal of tissue engineering

In vivo bone regeneration by differently designed titanium membrane with or without surface treatment: a study in rat calvarial defects.

Yong-Seok Jang, So-Hee Moon, Thuy-Duong Thi Nguyen, Min-Ho Lee, Tae-Ju Oh, A-Lum Han, Tae-Sung Bae

Open access · goldAbstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Yong-Seok JangDepartment of Dental Biomaterials, Institute of Oral Bioscience and Institute of Biodegradable Material, BK21 Plus Project, School of Dentistry, Chonbuk National University, Jeonju, South Korea.
So-Hee MoonDepartment of Periodontology, School of Dentistry, Chonbuk National University, Jeonju, South Korea.
Thuy-Duong Thi NguyenFaculty of Odonto-Stomatology, Hue University of Medicine and Pharmacy, Hue, Vietnam.
Min-Ho LeeDepartment of Dental Biomaterials, Institute of Oral Bioscience and Institute of Biodegradable Material, BK21 Plus Project, School of Dentistry, Chonbuk National University, Jeonju, South Korea.
Tae-Ju OhDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI, USA.
A-Lum HanDepartment of Family Medicine, College of Medicine, Wonkwang University, Iksan, South Korea.
Tae-Sung BaeDepartment of Dental Biomaterials, Institute of Oral Bioscience and Institute of Biodegradable Material, BK21 Plus Project, School of Dentistry, Chonbuk National University, Jeonju, South Korea.ORCID https://orcid.org/0000-0002-8307-4544
Jeonbuk National University · KRHue University · VNUniversity of Michigan · USWonkwang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current objective was to evaluate six groups of titanium membranes in a rat calvarial defect model, regarding the surface treatment with or without calcium-phosphate coating and surface topography with no, small, or large holes. Critical size defects (Ф = 8 mm, n = 42) were surgically created in rat calvaria, and then were treated by one of the six groups. Biopsies were obtained at 4 weeks (n = 5 per group) for micro-computed tomography and histomorphometric analyses. Fluorochrome bone markers were injected in two rats each group at 1 (Alizarin red), 3 (Calcein green) and 5 weeks (Oxytetracyclin yellow), followed by histological examination at 7 weeks to assess bone regeneration dynamic. At 4 weeks, the highest bone volume was observed in no-hole groups independent of surface treatment (

Indexed as

bone regenerationCalcium-phosphate coatingrat calvarial modelsurface treatmenttitanium membrane

Identifiers

PMID30834101
PMCPMC6396043
OpenAlexW2919967323

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.