ArticleIranian journal of basic medical sciences2019
Cocoa administration may accelerate orthodontic tooth movement by inducing osteoclastogenesis in rats.
Article in Iranian journal of basic medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 14 citations in OpenAlex.
- Potency of hyaluronic acid from eggshell-membrane for open gingival embrasure reconstruction following orthodontic tooth movement (a histomorphological study).Dental research journal · 2022Article
- Postorthodontic Relapse Prevention by Administration of Grape Seed (Vitis vinifera) Extract Containing Cyanidine in Rats.European journal of dentistry · 2019Article
- Wheat seeds can delay orthodontic tooth movement by blocking osteoclastogenesis in rats.Clinical, cosmetic and investigational dentistry · 2019Article
- The effect of cacao bean extracts on the prevention of periodontal tissue breakdown in diabetic rats with orthodontic tooth movements.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the effect of cocoa on orthodontic tooth movement (OTM) rate, osteoprotegerin (OPG), and receptor activator of nuclear factor κ β ligand (RANKL) levels after OTM. MATERIALS AND
methodsA total of 24 Sprague-Dawley rats were included in the study. They were equally divided into two groups: cocoa and control. The upper incisors of all rats were subjected to 35 cN orthodontic force and moved distally with a stainless steel 3-spin coil spring. During OTM, the cocoa group was given 4.8 g of unsweetened cocoa once a day. At 4 subsequent time points (0, 1, 7, and 14 days), the OTM rate was determined by measuring the distance between the mesial tips using a digital caliper, while OPG and RANKL levels were examined based on their gingival crevicular fluid through specific enzyme-linked immunosorbent assay (ELISA). Data gathered were analyzed through independent t-test (
resultsThe OTM rate of the cocoa group was significantly higher than that of the control group on days 1, 7, and 14 (
conclusionThese results indicate that cocoa has the potential effect to modulate the OTM rate by inducing osteoclastogenesis, which suppresses the OPG level and stimulates the RANKL level, in rats.
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