Evidence map›Paper›PMID 30833861›Full record

ReviewClinics in colon and rectal surgery2019

Pain Management in Enhanced Recovery after Surgery (ERAS) Protocols.

J Creswell Simpson, Xiaodong Bao, Aalok Agarwala

5 registry-linked trialsAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinics in colon and rectal surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 125 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 13 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04705480 phase4completednot on this mapstarted 2021, after this paper: background citation

Pregabalin vs. Gabapentin on Reducing Opioid Usage in Trauma Patients

TypeinterventionalSponsorCAMC Health SystemRan2021 to 2024Enrolled109ConditionsAnalgesics, Gabapentin, Injuries, NarcoticsArmsPregabalin 50mg, Gabapentin 300mg, Neither Pregabalin nor Gabapentin
NCT05248152 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Psychosocial and Psychophysical Factors Influencing the Effect of Preemptive Systemic Analgesia in Combination With Regional Anesthesia on Postoperative Pain Following Upper Limb Surgery

TypeinterventionalSponsorUniversity Medical Centre LjubljanaRan2022 to 2024Enrolled90ConditionsPostoperative PainArmsParacetamol and Ibuprofen, Pregabalin 150mg, Placebo
NCT05972018 phase4recruitingnot on this mapstarted 2023, after this paper: background citation

Liposomal Bupivacaine/Bupivacaine A Single-Dose Bilateral Rectus Sheath Blocks Versus Ropivacaine in Bilateral Rectus Sheath Blocks And Catheters With Intermittent Hourly Boluses.

TypeinterventionalSponsorHartford HospitalRan2023 to 2026Enrolled14ConditionsAortic Aneurysm, Abdominal, Abdominal Aortic Occlusion, Aortoiliac Occlusive Disease, Aortic DiseasesArmsLiposomal bupivacaine, Ropivacaine, Bupivacain
NCT06231355 phase4completednot on this mapstarted 2024, after this paper: background citation

Efficacy of Liposomal Bupivacaine Versus Conventional Bupivacaine for Pain Control in Patients Undergoing Laparoscopic Radical Nephrectomy: A Pilot Randomized Trial

TypeinterventionalSponsorPeking University First HospitalRan2024 to 2024Enrolled61ConditionsLocal Anesthetics, Analgesia, Regional Block, Paravertebral BlockArmsPerforming paravertebral nerve block with lipo-bupivacaine, Performing paravertebral nerve block with bupivacaine
NCT07575243 completednot on this mapstarted 2024, after this paper: background citation

A Comprehensive Enhanced Recovery After Surgery (ERAS) Protocol for Thyroidectomy

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled143ConditionsThyroid Diseases, Goiter, Thyroid NeoplasmsArmsEnhanced Recovery After Surgery protocol, Conventional perioperative care
3 · Its place in the literature

Who cites it

125 citing papers in PubMed, 13 syntheses or guidelines pooled it.

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65 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J Creswell SimpsonDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Xiaodong BaoDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Aalok AgarwalaDepartment of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain control is an integral part of Enhanced Recovery after Surgery (ERAS) protocols for colorectal surgery. While opioid therapy remains the mainstay of therapy for postsurgical pain, opioids have undesired side effects including delayed recovery of bowel function, respiratory depression, and postoperative nausea and vomiting. A variety of nonopioid systemic medical therapies as well as regional and neuraxial techniques have been described as improving pain control while reducing opioid use. Multimodal and preemptive analgesia as part of an ERAS protocol facilitates early mobility and early return of bowel function and decreases postoperative morbidity. In this review, we examine several multimodal therapies and their impact on postoperative analgesia, opioid use, and recovery for patients undergoing colorectal surgery.

Indexed as

colorectal surgeryERASmultimodal analgesiapain management

Identifiers

PMID30833861
PMCPMC6395101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.