ArticleWorld journal of gastroenterology2019
Two-year delay in ulcerative colitis diagnosis is associated with anti-tumor necrosis factor alpha use.
Article in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic delay in adult inflammatory bowel disease: A systematic review.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023Pooled it
- Impact of Delayed Diagnosis in IBD on Clinical Outcomes and Healthcare Delivery.Diagnostics (Basel, Switzerland) · 2026Article
- Possible underdiagnosis of ulcerative colitis in tertiary care can affect medication use and access to healthcare facilities.Frontiers in immunology · 2026Article
- Role of 5-aminosalicylic acid in ulcerative colitis management in 8 Asian territories: a physician survey.Intestinal research · 2025Article
- Genome-Wide DNA Methylation Identifies Potential Disease-Specific Biomarkers and Pathophysiologic Mechanisms in Irritable Bowel Syndrome, Inflammatory Bowel Disease, and Celiac Disease.Neurogastroenterology and motility · 2025Article
- Associations between prior healthcare use, time to diagnosis, and clinical outcomes in inflammatory bowel disease: a nationally representative population-based cohort study.BMJ open gastroenterology · 2024Article
- Article
- Diagnostic Delay of Inflammatory Bowel Disease Is Significantly Higher in Public versus Private Health Care System in Mexican Patients.Inflammatory intestinal diseases · 2022Article
- Screening of characteristic genes in ulcerative colitis by integrating gene expression profiles.BMC gastroenterology · 2021Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUlcerative colitis (UC) is an uncommon inflammatory bowel disease (IBD). However, its incidence has recently increased in South Korea. Moreover, UC diagnoses are frequently delayed, and the relationship between diagnostic delay and UC prognosis has not been extensively studied in South Korean patients.
aimTo identify meaningful diagnostic delay affecting UC prognosis and to evaluate risk factors associated with diagnostic delay in South Korean patients.
methodsMedical records of 718 patients with UC who visited the outpatient clinic of six university hospitals in South Korea were reviewed; 167 cases were excluded because the first symptom date was unknown. We evaluated the relationship between the prognosis and a diagnostic delay of 3, 6, 12, 18, and 24 mo by comparing the prognostic factors [anti-tumor necrosis factor (TNF)-α use, admission history due to acute flare-ups, frequent admission due to flare-ups, surgery associated with UC, and the clinical remission state at the latest follow-up] at each diagnostic interval.
resultsThe mean diagnostic interval was 223.3 ± 483.2 d (median, 69 d; 75
conclusionA diagnostic delay > 24 mo was associated with increased anti-TNFα use. Age < 60 years at diagnosis, smoking history, and misdiagnosis of hemorrhoids were risk factors for delayed diagnosis.
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